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- ItemSPEED: an integrated, smartphone-operated, handheld digital PCR Device for point-of-care testing(Springer Nature, 2024-05-20) Zhang, Haoqing; Liu, Xiaocheng; Wang, Xinlu; Yan, Zhiqiang; Xu, Ying; Gaňová, Martina; Řezníček, Tomáš; Korabečná, Marie; Neužil, PavelThis study elaborates on the design, fabrication, and data analysis details of SPEED, a recently proposed smartphone-based digital polymerase chain reaction (dPCR) device. The dPCR chips incorporate partition diameters ranging from 50 mu m to 5 mu m, and these partitions are organized into six distinct blocks to facilitate image processing. Due to the superior thermal conductivity of Si and its potential for mass production, the dPCR chips were fabricated on a Si substrate. A temperature control system based on a high-power density Peltier element and a preheating/cooling PCR protocol user interface shortening the thermal cycle time. The optical design employs four 470 nm light-emitting diodes as light sources, with filters and mirrors effectively managing the light emitted during PCR. An algorithm is utilized for image processing and illumination nonuniformity correction including conversion to a monochromatic format, partition identification, skew correction, and the generation of an image correction mask. We validated the device using a range of deoxyribonucleic acid targets, demonstrating its potential applicability across multiple fields. Therefore, we provide guidance and verification of the design and testing of the recently proposed SPEED device.
- Item1 V Tunable High-Quality Universal Filter Using Multiple-Input Operational Transconductance Amplifiers(MDPI, 2024-05-09) Kumngern, Montree; Khateb, Fabian; Kulej, Tomasz; Knobnob, BoonyingThis paper presents a new multiple-input single-output voltage-mode universal filter employing four multiple-input operational transconductance amplifiers (MI-OTAs) and three grounded capacitors suitable for low-voltage low-frequency applications. The quality factor (Q) of the filter functions can be tuned by both the capacitance ratio and the transconductance ratio. The multiple inputs of the OTA are realized using the bulk-driven multiple-input MOS transistor technique. The MI-OTA-based filter can also offer many filtering functions without additional circuitry requirements, such as an inverting amplifier to generate an inverted input signal. The proposed filter can simultaneously realize low-pass, high-pass, band-pass, band-stop, and all-pass responses, covering both non-inverting and inverting transfer functions in a single topology. The natural frequency and the quality factors of all the filtering functions can be controlled independently. The natural frequency can also be electronically controlled by tuning the transconductances of the OTAs. The proposed filter uses a 1 V supply voltage, consumes 120 mu W of power for a 5 mu A setting current, offers 40 dB of dynamic range and has a third intermodulation distortion of -43.6 dB. The performances of the proposed circuit were simulated using a 0.18 mu m TSMC CMOS process in the Cadence Virtuoso System Design Platform to confirm the performance of the topology.
- ItemCurrent-Mode Active Filter Using EX-CCCII(MDPI, 2024-05-25) Kumngern, Montree; Khateb, Fabian; Kulej, Tomasz; Tooprakai, SiraphopThis paper presents a novel multiple-input and multiple-output current-mode universal analog filter with electronic tuning capability. The proposed circuit uses a single second-generation current-controlled current conveyor with extra-X terminals (EX-CCCII) and two grounded capacitors. The filter can offer five standard filtering functions, namely low-pass, high-pass, band-pass, band-stop, all-pass responses, in the same circuit without changing the internal configuration of the filter by selecting appropriate input and output signals. To obtain the five standard filtering functions, inverted input signal and input matching conditions are absent. The natural frequency of all filter responses can be electronically controlled. The proposed circuit was simulated by SPICE using 0.18 mu m CMOS process from Taiwan Semiconductor Manufacturing Company (TSMC). The results of experiments using the integrated circuit operational amplifier AD844 confirm the functionality of the new filter.
- ItemElectrical properties of epoxy/graphite flakes microcomposite at the percolation threshold concentration(IOP Publishing Ltd, 2024-04-17) Alsoud, Ammar Awadallah Ahmad; Daradkeh, Samer; Shaheen, Adel A; Al-Hroub, Qasim Amjad; Knápek, Alexandr; Mousa, Marwan; Sobola, DinaraThe electrical properties and activation energy of epoxy/graphite flakes (GFs) micro-composite with different content of GFs (0.0625-1 wt%) were studied for electrical properties using Novocontrol Alpha Analyser (10-2 Hz-107 Hz). GFs sizes ranged from (100 nm to 10 mu m). The analysis was performed by scanning electron microscopy (SEM), x-ray photoelectron spectroscopy (XPS), visible spectrum reflectance spectra (VIS) spectra, and Fourier Transform Infrared spectra (FTIR) spectroscopy. Increasing GFs content caused multiple changes in electrical characteristics. At 0.0625 wt%, all electrical properties noticeably increased. But at 0.125 to 0.25 wt%, immobilized nanolayers were formed leading to decreased permittivity, dielectric loss (tan(delta)), quality factor (Q-factor), capacitance, conductivity, and figure of merit (F-factor). At 0.25 wt%, the epoxy microcomposite had lower permittivity, tan(delta), conductivity, and capacitance compared with unfilled epoxy. With 0.5 wt% of GFs, signified the percolation threshold, initiating a rise in permittivity, conductivity, capacitance, and tan(delta), accompanied by the closer proximity of grain boundaries, facilitating the formation of conductive channels. At a concentration of 1 wt% of GFs, the establishment of continuous interfacial conductive pathways resulted in a remarkable augmentation of all dielectric properties. The Cole-Cole analysis has been employed to investigate variations in epoxy/GFs microcomposites based on concentration levels.
- ItemAutomatic test-bench for SiC power devices using LabVIEW(SLOVAK UNIV TECHNOLOGY, 2024-04-01) Leuchter, Jan; Pham, Ngoc Nam; Nguyen, Huy HoangThis paper is devoted to the improvement existing models of electronics devices, which are used in powers electronics as switching devices, and investigate a LabVIEW-based automatic test-bench for Silicon carbide (SiC) power devices. In recent years, power electronic devices are required to be capable handle with higher voltage, leads to development of new generation of power electronic devices, such as SiC devices. However, using a simulation platform, such as Spice, to diminish the complexity of power electronic design with these new devices is hindered by the lack of precise models. The proposed test-bench enables not only measuring static characteristics of SiC power devices, but also extracting key parameters required by simulations. These extracted parameters are then employed in the existing device model, and the simulation results which are based on the model with original parameters and models with extracted parameters are compared with measured results. The comparison clearly demonstrates that parameters obtained from the proposed test-bench significantly enhance the Spice model.