Apoferritin modified magnetic particles as doxorubicin carriers for anticancer drug delivery

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dc.contributor.authorBlažková, Ivacs
dc.contributor.authorNguyen, Hoai Vietcs
dc.contributor.authorDostálová, Simonacs
dc.contributor.authorKopel, Pavelcs
dc.contributor.authorStanisavljevic, Majacs
dc.contributor.authorVaculovičová, Markétacs
dc.contributor.authorStiborová, Mariecs
dc.contributor.authorEckschlager, Tomášcs
dc.contributor.authorKizek, Renécs
dc.contributor.authorAdam, Vojtěchcs
dc.coverage.issue7cs
dc.coverage.volume14cs
dc.date.issued2013-06-27cs
dc.description.abstractMagnetic particle mediated transport in combination with nanomaterial based drug carrier has a great potential for targeted cancer therapy. In this study, doxorubicin encapsulation into the apoferritin and its conjugation with magnetic particles was investigated by capillary electrophoresis with laser-induced fluorescence detection (CE-LIF). The quantification of encapsulated doxorubicin was performed by fluorescence spectroscopy and compared to CE-LIF. Moreover, the significant enhancement of the doxorubicin signal was observed by addition of methanol into the sample solutionen
dc.description.abstractMagnetic particle mediated transport in combination with nanomaterial based drug carrier has a great potential for targeted cancer therapy. In this study, doxorubicin encapsulation into the apoferritin and its conjugation with magnetic particles was investigated by capillary electrophoresis with laser-induced fluorescence detection (CE-LIF). The quantification of encapsulated doxorubicin was performed by fluorescence spectroscopy and compared to CE-LIF. Moreover, the significant enhancement of the doxorubicin signal was observed by addition of methanol into the sample solutionen
dc.formattextcs
dc.format.extent13391-13402cs
dc.format.mimetypeapplication/pdfcs
dc.identifier.citationINTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2013, vol. 14, issue 7, p. 13391-13402.en
dc.identifier.doi10.3390/ijms140713391cs
dc.identifier.issn1661-6596cs
dc.identifier.orcid0000-0003-4216-9544cs
dc.identifier.orcid0000-0002-6771-1304cs
dc.identifier.orcid0000-0002-8527-286Xcs
dc.identifier.other100937cs
dc.identifier.researcheridE-5711-2012cs
dc.identifier.researcheridE-5583-2016cs
dc.identifier.researcheridD-7686-2012cs
dc.identifier.scopus6603604023cs
dc.identifier.urihttp://hdl.handle.net/11012/70079
dc.language.isoencs
dc.publisherMDPIcs
dc.relation.ispartofINTERNATIONAL JOURNAL OF MOLECULAR SCIENCEScs
dc.relation.urihttp://www.mdpi.com/1422-0067/14/7/13391cs
dc.rightsCreative Commons Attribution 3.0 Unportedcs
dc.rights.accessopenAccesscs
dc.rights.sherpahttp://www.sherpa.ac.uk/romeo/issn/1661-6596/cs
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/cs
dc.subjectMagnetic particleen
dc.subjectdoxorubicinen
dc.subjectfluorescence spectroscopyen
dc.subjectMagnetic particle
dc.subjectdoxorubicin
dc.subjectfluorescence spectroscopy
dc.titleApoferritin modified magnetic particles as doxorubicin carriers for anticancer drug deliveryen
dc.title.alternativeApoferritin modified magnetic particles as doxorubicin carriers for anticancer drug deliveryen
dc.type.driverarticleen
dc.type.statusPeer-revieweden
dc.type.versionpublishedVersionen
sync.item.dbidVAV-100937en
sync.item.dbtypeVAVen
sync.item.insts2025.10.14 14:11:08en
sync.item.modts2025.10.14 09:49:48en
thesis.grantorVysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií. Ústav mikroelektronikycs
thesis.grantorVysoké učení technické v Brně. Středoevropský technologický institut VUT. Chytré nanonástrojecs

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