Serum metallothioneins in childhood tumours – A potential prognostic marker

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dc.contributor.authorKruseová, Jarmilacs
dc.contributor.authorHynek, Davidcs
dc.contributor.authorAdam, Vojtěchcs
dc.contributor.authorKizek, Renécs
dc.contributor.authorPrůša, Richardcs
dc.contributor.authorHraběta, Jancs
dc.contributor.authorEckschlager, Tomášcs
dc.coverage.issue6cs
dc.coverage.volume14cs
dc.date.issued2013-06-06cs
dc.description.abstractMetallothioneins (MT) are low molecular weight, cysteine-rich proteins maintaining metal ions homeostasis. They play a role in carcinogenesis and may also cause chemoresistance. The aim of the study was to explore the importance of MT serum levels in children suffering from malignant tumours. This prospective study involves examination of 865 samples from 172 patients with malignant tumours treated from 2008 to 2011 at University Hospital Motol. MT serum levels were determined using differential pulse voltammetry–Brdicka reactionen
dc.description.abstractMetallothioneins (MT) are low molecular weight, cysteine-rich proteins maintaining metal ions homeostasis. They play a role in carcinogenesis and may also cause chemoresistance. The aim of the study was to explore the importance of MT serum levels in children suffering from malignant tumours. This prospective study involves examination of 865 samples from 172 patients with malignant tumours treated from 2008 to 2011 at University Hospital Motol. MT serum levels were determined using differential pulse voltammetry–Brdicka reactionen
dc.formattextcs
dc.format.extent12170-12185cs
dc.format.mimetypeapplication/pdfcs
dc.identifier.citationINTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2013, vol. 14, issue 6, p. 12170-12185.en
dc.identifier.doi10.3390/ijms140612170cs
dc.identifier.issn1661-6596cs
dc.identifier.orcid0000-0002-7318-6470cs
dc.identifier.orcid0000-0002-8527-286Xcs
dc.identifier.other101188cs
dc.identifier.researcheridE-5702-2012cs
dc.identifier.researcheridD-7686-2012cs
dc.identifier.urihttp://hdl.handle.net/11012/70082
dc.language.isoencs
dc.publisherMDPIcs
dc.relation.ispartofINTERNATIONAL JOURNAL OF MOLECULAR SCIENCEScs
dc.relation.urihttp://www.mdpi.com/1422-0067/14/6/12170cs
dc.rightsCreative Commons Attribution 3.0 Unportedcs
dc.rights.accessopenAccesscs
dc.rights.sherpahttp://www.sherpa.ac.uk/romeo/issn/1661-6596/cs
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/cs
dc.subjectmetallothioneinen
dc.subjectprognostic markeren
dc.subjectcysteineen
dc.subjectchemoresistanceen
dc.subjectmetallothionein
dc.subjectprognostic marker
dc.subjectcysteine
dc.subjectchemoresistance
dc.titleSerum metallothioneins in childhood tumours – A potential prognostic markeren
dc.title.alternativeSerum metallothioneins in childhood tumours – A potential prognostic markeren
dc.type.driverarticleen
dc.type.statusPeer-revieweden
dc.type.versionpublishedVersionen
sync.item.dbidVAV-101188en
sync.item.dbtypeVAVen
sync.item.insts2025.10.14 14:11:09en
sync.item.modts2025.10.14 10:04:51en
thesis.grantorVysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií. Ústav mikroelektronikycs
thesis.grantorVysoké učení technické v Brně. Středoevropský technologický institut VUT. Chytré nanonástrojecs

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