A low-cost picowatt calorimeter using a flexible printed circuit board

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dc.contributor.authorZhu, Hanliangcs
dc.contributor.authorZhang, Yuecs
dc.contributor.authorWang, Lancs
dc.contributor.authorBrodský, Jancs
dc.contributor.authorGablech, Imrichcs
dc.contributor.authorFeng, Jianguocs
dc.contributor.authorYan, Qi-Longcs
dc.contributor.authorYang, Shujiecs
dc.contributor.authorLee, Luke P.cs
dc.contributor.authorNeužil, Pavelcs
dc.coverage.issueMarchcs
dc.coverage.volume16cs
dc.date.accessioned2025-05-30T08:56:50Z
dc.date.available2025-05-30T08:56:50Z
dc.date.issued2025-03-27cs
dc.description.abstractCalorimetry is crucial in biology, chemistry, physics, and pharmaceutical research, enabling the detection of heat changes at nanowatt and picowatt levels. However, traditional calorimetry systems are often limited by high costs and complex fabrication processes. Here, we reduce the cost and fabrication complexity of microcalorimeters by utilizing widely available flexible printed circuit manufacturing processes. This device achieves temperature and power resolutions of 6 K and 654pW in vacuum. Its feasibility is validated across a wide range of measurements, including salt crystallization, protein crystallization, and cellular metabolism. Our concept enhances the accessibility of microcalorimeters for high-resolution thermal analysis, which is challenging for conventional calorimeters.en
dc.formattextcs
dc.format.extent1-13cs
dc.format.mimetypeapplication/pdfcs
dc.identifier.citationNATURE COMMUNICATIONS. 2025, vol. 16, issue March, p. 1-13.en
dc.identifier.doi10.1038/s41467-025-58025-9cs
dc.identifier.issn2041-1723cs
dc.identifier.orcid0000-0002-5656-3158cs
dc.identifier.orcid0000-0003-4218-1287cs
dc.identifier.other197504cs
dc.identifier.researcheridGYJ-6288-2022cs
dc.identifier.researcheridH-7835-2016cs
dc.identifier.scopus57212587388cs
dc.identifier.scopus55091127400cs
dc.identifier.urihttps://hdl.handle.net/11012/251185
dc.language.isoencs
dc.publisherNature Portfoliocs
dc.relation.ispartofNATURE COMMUNICATIONScs
dc.relation.urihttps://www.nature.com/articles/s41467-025-58025-9cs
dc.rightsCreative Commons Attribution-NonCommercial-NoDerivatives 4.0 Internationalcs
dc.rights.accessopenAccesscs
dc.rights.sherpahttp://www.sherpa.ac.uk/romeo/issn/2041-1723/cs
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/cs
dc.subjectcalorimetryen
dc.subjectthermal analysisen
dc.subjectflexible printed circuit boarden
dc.titleA low-cost picowatt calorimeter using a flexible printed circuit boarden
dc.type.driverarticleen
dc.type.statusPeer-revieweden
dc.type.versionpublishedVersionen
sync.item.dbidVAV-197504en
sync.item.dbtypeVAVen
sync.item.insts2025.05.30 10:56:49en
sync.item.modts2025.05.30 10:33:34en
thesis.grantorVysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií. Ústav mikroelektronikycs
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