Study of cholesterol’s effect on the properties of catanionic vesicular systems: comparison of light-scattering results with ultrasonic and fluorescence spectroscopy

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dc.contributor.authorHavlíková, Martinacs
dc.contributor.authorSzabová, Janacs
dc.contributor.authorJugl, Adamcs
dc.contributor.authorMravcová, Ludmilacs
dc.contributor.authorChang, Chien-Hsiangcs
dc.contributor.authorHuang, Po-Sungcs
dc.contributor.authorPekař, Miloslavcs
dc.contributor.authorMravec, Filipcs
dc.coverage.issue1cs
dc.coverage.volume607cs
dc.date.issued2020-12-20cs
dc.description.abstractThis work is focused on the study of properties associated with the effect of cholesterol levels on the stability of vesicular systems based on the ion pair amphiphile hexadecyltrimethylammonium-dodecylsulphate (HTMA-DS) at laboratory temperature. The HTMA-DS catanionic system was doped with dioctadecyldimethylammonium chloride in a 9:1 molar ratio and cholesterol in the amount of 0, 3, 13, 23, 33, 43, 53, 63, and 73mol.% was added. In this system, the size distributions were studied using the dynamic light-scattering technique and the zeta potential was determined. These standard techniques were supplemented by ultrasonic and fluorescence spectroscopy techniques. Due to low stability and high opalescence of samples, spectral techniques were used only for the samples with cholesterol content above 23mol.%. The results from High-Resolution Ultrasonic Spectroscopy and from Fluorescence Spectroscopy are in agreement. They equally point to a change in the amount of hydration water in the membrane, the largest amount of which is present in the samples with 43 and 53mol.% cholesterol. Using the light-scattering technique, the short-term stability of prepared vesicular systems was also observed over the first 36 days. Obtained results confirmed that the most stable systems are those containing 43 or 53mol.% of cholesterol.en
dc.formattextcs
dc.format.extent1-7cs
dc.format.mimetypeapplication/pdfcs
dc.identifier.citationColloids and Surfaces A: Physicochemical and Engineering Aspects. 2020, vol. 607, issue 1, p. 1-7.en
dc.identifier.doi10.1016/j.colsurfa.2020.125526cs
dc.identifier.issn0927-7757cs
dc.identifier.orcid0000-0002-1877-072Xcs
dc.identifier.orcid0000-0001-7638-8759cs
dc.identifier.orcid0000-0003-0602-2334cs
dc.identifier.orcid0000-0003-1011-6616cs
dc.identifier.orcid0000-0002-3878-0917cs
dc.identifier.orcid0000-0001-6114-4751cs
dc.identifier.other164858cs
dc.identifier.researcheridABA-2718-2020cs
dc.identifier.researcheridG-9690-2018cs
dc.identifier.researcheridG-7170-2015cs
dc.identifier.scopus25621742800cs
dc.identifier.scopus12039611100cs
dc.identifier.urihttp://hdl.handle.net/11012/196450
dc.language.isoencs
dc.publisherElsevier B.V.cs
dc.relation.ispartofColloids and Surfaces A: Physicochemical and Engineering Aspectscs
dc.relation.urihttps://www.sciencedirect.com/science/article/pii/S0927775720311195?via%3Dihubcs
dc.rightsCreative Commons Attribution-NonCommercial-NoDerivatives 4.0 Internationalcs
dc.rights.accessopenAccesscs
dc.rights.sherpahttp://www.sherpa.ac.uk/romeo/issn/0927-7757/cs
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/cs
dc.subjectIon pair amphiphileen
dc.subjectCatanionic vesiclesen
dc.subjectCholesterolen
dc.subjectHigh-resolution ultrasonic spectroscopyen
dc.subjecthydration wateren
dc.subjectFluorescence spectroscopy.en
dc.titleStudy of cholesterol’s effect on the properties of catanionic vesicular systems: comparison of light-scattering results with ultrasonic and fluorescence spectroscopyen
dc.type.driverarticleen
dc.type.statusPeer-revieweden
dc.type.versionacceptedVersionen
sync.item.dbidVAV-164858en
sync.item.dbtypeVAVen
sync.item.insts2025.02.03 15:37:56en
sync.item.modts2025.01.17 18:41:55en
thesis.grantorVysoké učení technické v Brně. Fakulta chemická. Centrum materiálového výzkumucs
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