Improving the strength of -TCP scaffolds produced by Digital Light Processing using two-step sintering

Abstract

Digital Light Processing is combined with two-step sintering to obtain bioactive scaffolds with improved strength and mechanical isotropy. Highly loaded photosensitive suspensions were prepared from beta-TCP powder to create scaffolds consisting of interpenetrating struts with two different designs. Two sintering methods were used: conventional sintering (CS) and two-step sintering (2SS). The latter resulted in a microstructure with uniformly shaped grains and reduced porosity. Their compressive strength was determined by uniaxial testing under two different load configurations, with the force applied parallel or perpendicular to the building plane of the scaffolds. Design optimisation and fine-tuning of the sintering process helped in reducing the presence of interlayer defects and minimise the shear-dominated fractures. Isotropic fracture behaviour was achieved, with similar central values of the Weibull distribution (49 +/- 1 MPa vs. 51 +/- 1 MPa) along both testing directions, showing a great potential for their use in load-bearing bone tissue engineering applications.Digital Light Processing is combined with two-step sintering to obtain bioactive scaffolds with improved strength and mechanical isotropy. Highly loaded photosensitive suspensions were prepared from beta-TCP powder to create scaffolds consisting of interpenetrating struts with two different designs. Two sintering methods were used: conventional sintering (CS) and two-step sintering (2SS). The latter resulted in a microstructure with uniformly shaped grains and reduced porosity. Their compressive strength was determined by uniaxial testing under two different load configurations, with the force applied parallel or perpendicular to the building plane of the scaffolds. Design optimisation and fine-tuning of the sintering process helped in reducing the presence of interlayer defects and minimise the shear-dominated fractures. Isotropic fracture behaviour was achieved, with similar central values of the Weibull distribution (49 +/- 1 MPa vs. 51 +/- 1 MPa) along both testing directions, showing a great potential for their use in load-bearing bone tissue engineering applications.