The effect of Benzothiazolone-2 on the expression of Metallothionein-3 in modulating Alzheimer's disease

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dc.contributor.authorRoy, Sudeepcs
dc.contributor.authorGumulec, Jaromírcs
dc.contributor.authorKumar, Akhilcs
dc.contributor.authorRaudenská, Martinacs
dc.contributor.authorBaig, Mohd Hassancs
dc.contributor.authorPolanská, Hanacs
dc.contributor.authorBalvan, Jancs
dc.contributor.authorGupta, Mansics
dc.contributor.authorBabula, Petrcs
dc.contributor.authorOdstrčilík, Jancs
dc.contributor.authorChoi, Inhocs
dc.contributor.authorProvazník, Valentýnacs
dc.contributor.authorMasařík, Michalcs
dc.coverage.issue9cs
dc.coverage.volume7cs
dc.date.issued2017-08-15cs
dc.description.abstractMetallothioneins (MTs) are a class of ubiquitously occurring low-molecular-weight cysteine- and metal-rich proteins containing sulfur-based metal clusters. MT-3 exhibits neuro-inhibitory activity. The possibility to enhance the expression of MT-3 or protect it from degradation is an attractive therapeutic target, because low levels of MT-3 were found in brains of Alzheimer's disease (AD) patients.en
dc.formattextcs
dc.format.extent1-9cs
dc.format.mimetypeapplication/pdfcs
dc.identifier.citationBrain and Behavior. 2017, vol. 7, issue 9, p. 1-9.en
dc.identifier.doi10.1002/brb3.799cs
dc.identifier.issn2162-3279cs
dc.identifier.orcid0000-0002-7825-0152cs
dc.identifier.orcid0000-0002-9658-3444cs
dc.identifier.orcid0000-0001-8529-552Xcs
dc.identifier.orcid0000-0001-7053-6183cs
dc.identifier.orcid0000-0002-3422-7938cs
dc.identifier.orcid0000-0003-1172-7195cs
dc.identifier.other139120cs
dc.identifier.researcheridD-7638-2012cs
dc.identifier.researcheridA-2237-2016cs
dc.identifier.researcheridF-4121-2012cs
dc.identifier.researcheridD-9920-2012cs
dc.identifier.scopus000000278250152cs
dc.identifier.scopus55769747816cs
dc.identifier.scopus35753651000cs
dc.identifier.scopus6701729526cs
dc.identifier.urihttp://hdl.handle.net/11012/69945
dc.language.isoencs
dc.publisherWiley Periodicalscs
dc.relation.ispartofBrain and Behaviorcs
dc.relation.urihttp://onlinelibrary.wiley.com/doi/10.1002/brb3.799/abstractcs
dc.rightsCreative Commons Attribution 4.0 Internationalcs
dc.rights.accessopenAccesscs
dc.rights.sherpahttp://www.sherpa.ac.uk/romeo/issn/2162-3279/cs
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/cs
dc.subjectAlzheimer’s Diseaseen
dc.subjectFlow Cytometryen
dc.subjectImmunodetectionen
dc.subjectMetallothionein-3en
dc.subjectMolecular Dynamicsen
dc.subjectqRT-PCRen
dc.titleThe effect of Benzothiazolone-2 on the expression of Metallothionein-3 in modulating Alzheimer's diseaseen
dc.type.driverarticleen
dc.type.statusPeer-revieweden
dc.type.versionpublishedVersionen
sync.item.dbidVAV-139120en
sync.item.dbtypeVAVen
sync.item.insts2025.02.03 15:40:05en
sync.item.modts2025.01.17 15:22:01en
thesis.grantorVysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií. Ústav biomedicínského inženýrstvícs
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