Adaptability of Electrospun PVDF Nanofibers in Bone Tissue Engineering

Simple item page
dc.contributor.authorHavlíková, Terezacs
dc.contributor.authorPapež, Nikolacs
dc.contributor.authorFohlerová, Zdenkacs
dc.contributor.authorKaspar, Pavelcs
dc.contributor.authorDallaev, Rashidcs
dc.contributor.authorČástková, Kláracs
dc.contributor.authorŢălu, Ştefancs
dc.coverage.issue3cs
dc.coverage.volume17cs
dc.date.accessioned2025-08-01T12:59:54Z
dc.date.available2025-08-01T12:59:54Z
dc.date.issued2025-01-25cs
dc.description.abstractThis study focused on the development of a suitable synthetic polymer scaffold for bone tissue engineering applications within the biomedical field. The investigation centered on electrospun polyvinylidene fluoride (PVDF) nanofibers, examining their intrinsic properties and biocompatibility with the human osteosarcoma cell line Saos-2. The influence of oxygen, argon, or combined plasma treatment on the scaffold’s characteristics was explored. A comprehensive design strategy is outlined for the fabrication of a suitable PVDF scaffold, encompassing the optimization of electrospinning parameters with rotating collector and plasma etching conditions to facilitate a subsequent osteoblast cell culture. The proposed methodology involves the fabrication of the PVDF tissue scaffold, followed by a rigorous series of fundamental analyses encompassing the structural integrity, chemical composition, wettability, crystalline phase content, and cell adhesion properties.en
dc.formattextcs
dc.format.extent23cs
dc.format.mimetypeapplication/pdfcs
dc.identifier.citationPolymers. 2025, vol. 17, issue 3, 23 p.en
dc.identifier.doi10.3390/polym17030330cs
dc.identifier.issn2073-4360cs
dc.identifier.orcid0000-0003-2297-2890cs
dc.identifier.orcid0000-0002-1232-2301cs
dc.identifier.orcid0000-0003-1757-2382cs
dc.identifier.orcid0000-0002-6823-5725cs
dc.identifier.orcid0000-0002-6343-6659cs
dc.identifier.other196640cs
dc.identifier.researcheridY-9823-2019cs
dc.identifier.researcheridA-6893-2013cs
dc.identifier.researcheridH-1293-2014cs
dc.identifier.researcheridAAE-8648-2020cs
dc.identifier.scopus57195963424cs
dc.identifier.scopus56516508200cs
dc.identifier.scopus57201461813cs
dc.identifier.urihttps://hdl.handle.net/11012/255386
dc.language.isoencs
dc.publisherMDPIcs
dc.relation.ispartofPolymerscs
dc.relation.urihttps://www.mdpi.com/2073-4360/17/3/330cs
dc.rightsCreative Commons Attribution 4.0 Internationalcs
dc.rights.accessopenAccesscs
dc.rights.sherpahttp://www.sherpa.ac.uk/romeo/issn/2073-4360/cs
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/cs
dc.subjectbiocompatibilityen
dc.subjectbone tissue engineeringen
dc.subjectbone regenerationen
dc.subjectcell–substrate interactionsen
dc.subjectelectrospinningen
dc.subjectnanofiber fabricationen
dc.subjectosteoblastsen
dc.subjectpiezoelectric polymeren
dc.subjectplasma treatmenten
dc.subjectpolyvinylidene fluorideen
dc.subjectscaffolden
dc.titleAdaptability of Electrospun PVDF Nanofibers in Bone Tissue Engineeringen
dc.type.driverarticleen
dc.type.statusPeer-revieweden
dc.type.versionpublishedVersionen
sync.item.dbidVAV-196640en
sync.item.dbtypeVAVen
sync.item.insts2025.08.01 14:59:54en
sync.item.modts2025.08.01 13:33:21en
thesis.grantorVysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií. Ústav fyzikycs
thesis.grantorVysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií. Ústav mikroelektronikycs
thesis.grantorVysoké učení technické v Brně. Středoevropský technologický institut VUT. Pokročilé keramické materiálycs
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
polymers1700330v2.pdf
Size:
7.75 MB
Format:
Adobe Portable Document Format
Description:
file polymers1700330v2.pdf
Download
Collections
Ústav fyziky
Pokročilé keramické materiály
Ústav mikroelektroniky