In Vivo Antibacterial Study of Zinc Phosphate-based Nanoparticles

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dc.contributor.authorKočiová, Silviacs
dc.contributor.authorValečková, Vendulacs
dc.contributor.authorBytešníková, Zuzanacs
dc.contributor.authorHorký, Pavelcs
dc.contributor.authorKopel, Pavelcs
dc.contributor.authorAdam, Vojtěchcs
dc.contributor.authorŠmerková, Kristýnacs
dc.date.issued2019-02-01cs
dc.description.abstractIn animal nutrition, the nanotechnology is mostly used for the preparation of nanominerals, especially trace minerals, due to their low bioavailability. These nanominerals also showed advantageous effects at lower doses compared to conventional minerals. In addition, nanominerals can improve digestive efficacy, immunity and overall performance in livestock. In that case, we suggested and synthesized four types of zinc phosphatebased nanoparticles (ZnNPs), which achieved a significant antibacterial activity. After successful in vitro testing, we realized also in vivo study. We investigated the effect of zinc nanoparticles on rats after oral administration. Among others, the influence on total aerobic bacteria and coliforms in rat feces at day 10 or day 30 of treatment was monitored. In general, it has been observed a decrease of total aerobic and coliform bacteria population compared to untreated control group.en
dc.formattextcs
dc.format.extent511-516cs
dc.format.mimetypeapplication/pdfcs
dc.identifier.citationNANOCON 2018. 2019, p. 511-516.en
dc.identifier.isbn978-80-87294-89-5cs
dc.identifier.orcid0000-0003-4216-9544cs
dc.identifier.orcid0000-0002-8527-286Xcs
dc.identifier.orcid0000-0002-1667-7660cs
dc.identifier.other156259cs
dc.identifier.researcheridE-5711-2012cs
dc.identifier.researcheridD-7686-2012cs
dc.identifier.scopus6603604023cs
dc.identifier.urihttp://hdl.handle.net/11012/178356
dc.language.isoencs
dc.publisherTangercs
dc.relation.ispartofNANOCON 2018cs
dc.relation.urihttps://nanocon2018.tanger.cz/cz/cs
dc.rights(C) Tangercs
dc.rights.accessopenAccesscs
dc.subjectAntibioticsen
dc.subjectantimicrobial activityen
dc.subjectzinc nanoparticlesen
dc.subjectnanomineralsen
dc.subjectratsen
dc.titleIn Vivo Antibacterial Study of Zinc Phosphate-based Nanoparticlesen
dc.type.driverconferenceObjecten
dc.type.statusPeer-revieweden
dc.type.versionpublishedVersionen
sync.item.dbidVAV-156259en
sync.item.dbtypeVAVen
sync.item.insts2025.02.03 15:49:48en
sync.item.modts2025.01.17 16:38:17en
thesis.grantorVysoké učení technické v Brně. Středoevropský technologický institut VUT. Chytré nanonástrojecs
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