From chip-in-a-lab to lab-on-a-chip: towards a single handheld electronic system for multiple application-specific lab-on-a-chip (ASLOC)

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dc.contributor.authorNeužil, Pavelcs
dc.coverage.issue2168cs
dc.coverage.volume14cs
dc.date.issued2014-03-25cs
dc.description.abstractWe present a portable, battery-operated and application-specific lab-on-a-chip (ASLOC) system that can be easily configured for a wide range of lab-on-a-chip applications. It is based on multiplexed electrical current detection that serves as the sensing system. We demonstrate different configurations to perform most detection schemes currently in use in LOC systems, including some of the most advanced such as nanowire-based biosensing, surface plasmon resonance sensing, electrochemical detection and realtime PCR. The complete system is controlled by a single chip and the collected information is stored in situ, with the option of transferring the data to an external display by using a USB interface. In addition to providing a framework for truly portable real-life developments of LOC systems, we envisage that this system will have a significant impact on education, especially since it can easily demonstrate the benefits of integrated microanalytical systems.en
dc.description.abstractWe present a portable, battery-operated and application-specific lab-on-a-chip (ASLOC) system that can be easily configured for a wide range of lab-on-a-chip applications. It is based on multiplexed electrical current detection that serves as the sensing system. We demonstrate different configurations to perform most detection schemes currently in use in LOC systems, including some of the most advanced such as nanowire-based biosensing, surface plasmon resonance sensing, electrochemical detection and realtime PCR. The complete system is controlled by a single chip and the collected information is stored in situ, with the option of transferring the data to an external display by using a USB interface. In addition to providing a framework for truly portable real-life developments of LOC systems, we envisage that this system will have a significant impact on education, especially since it can easily demonstrate the benefits of integrated microanalytical systems.en
dc.formattextcs
dc.format.extent2168-2176cs
dc.format.mimetypeapplication/pdfcs
dc.identifier.citationLab on a chip. 2014, vol. 14, issue 2168, p. 2168-2176.en
dc.identifier.doi10.1039/c4lc00310acs
dc.identifier.issn1473-0197cs
dc.identifier.other115141cs
dc.identifier.urihttp://hdl.handle.net/11012/61762
dc.language.isoencs
dc.publisherRoyal Society of Chemistrycs
dc.relation.ispartofLab on a chipcs
dc.relation.urihttp://pubs.rsc.org/en/Content/ArticleLanding/2014/LC/C4LC00310Acs
dc.rightsCreative Commons Attribution 3.0 Unportedcs
dc.rights.accessopenAccesscs
dc.rights.sherpahttp://www.sherpa.ac.uk/romeo/issn/1473-0197/cs
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/cs
dc.subjectLOCen
dc.subjectmicroTASen
dc.subjectPCRen
dc.subjectelectrochemistryen
dc.subjectportable POC applications.en
dc.subjectLOC
dc.subjectmicroTAS
dc.subjectPCR
dc.subjectelectrochemistry
dc.subjectportable POC applications.
dc.titleFrom chip-in-a-lab to lab-on-a-chip: towards a single handheld electronic system for multiple application-specific lab-on-a-chip (ASLOC)en
dc.title.alternativeFrom chip-in-a-lab to lab-on-a-chip: towards a single handheld electronic system for multiple application-specific lab-on-a-chip (ASLOC)en
dc.type.driverarticleen
dc.type.statusPeer-revieweden
dc.type.versionpublishedVersionen
sync.item.dbidVAV-115141en
sync.item.dbtypeVAVen
sync.item.insts2025.10.14 15:17:01en
sync.item.modts2025.10.14 10:24:59en
thesis.grantorVysoké učení technické v Brně. Středoevropský technologický institut VUT. Chytré nanonástrojecs

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