Evaluation of cytotoxicity of biphasic TiO2 nanoparticles with organic surface coatings
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Date
2019-01-02
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Mark
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Mendel University in Brno
Abstract
Titanium dioxide nanoparticles (TiO2 NPs) are used in lots of human applications because of
their extraordinary nano scaled properties. Particularly, due to their photoprotective properties, they are
used in topical dermatologic preparation and also as white pigment. Due to these properties their use in
human life is more and more frequent. Despite the fact that nano dimension brings various beneficial
properties, it could bring also bad features. Therefore, in this study, we evaluated a cytotoxicity of two
types of biphasic TiO2 NPs using distinct cells of epithelial origin. We found that TiO2 NPs can induce
cytotoxic stress resulting in fragmentation of DNA.
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Peer-reviewed
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en
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(C) Mendel University in Brno