Utilizing of square wave voltammetry to detect flavonoids in the presence of human urine

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dc.contributor.authorAdam, Vojtěchcs
dc.contributor.authorHubálek, Jaromírcs
dc.contributor.authorBeklová, Miroslavacs
dc.contributor.authorTrnková, Libušecs
dc.contributor.authorKizek, Renécs
dc.coverage.issue10cs
dc.coverage.volume7cs
dc.date.accessioned2017-10-12T10:46:07Z
dc.date.available2017-10-12T10:46:07Z
dc.date.issued2007-10-15cs
dc.description.abstractAbout biological affecting of flavonoids on animal organisms is known less, thus we selected flavonoids, flavanones and flavones, and their glycosides, which were examined as potential inducers of cytochrome(s) P450 when administrated by gavages into experimental male rats. The study was focused on induction of CYP1A1, the major cytochrome P450 involved in carcinogen activation. The data obtained demonstrate the necessity of taking into account not only ability of flavonoids to bind to Ah receptor (induction factor) but also to concentrate on their distribution and metabolism (including colon microflora) in the body. After that we examined certain flavonoids as potential inducers of cytochrome P450, we wanted to suggest and optimize suitable electrochemical technique for determination of selected flavonoids (quercetin, quercitrin, rutin, chrysin and diosmin) in body liquids. For these purposes, we selected square wave voltannetry using carbon paste electrode.en
dc.formattextcs
dc.format.extent2402-2418cs
dc.format.mimetypeapplication/pdfcs
dc.identifier.citationSENSORS. 2007, vol. 7, issue 10, p. 2402-2418.en
dc.identifier.doi10.3390/s7102402cs
dc.identifier.issn1424-8220cs
dc.identifier.other49680cs
dc.identifier.urihttp://hdl.handle.net/11012/70075
dc.language.isoencs
dc.publisherMDPIcs
dc.relation.ispartofSENSORScs
dc.relation.urihttp://www.mdpi.com/1424-8220/7/10/2402cs
dc.rightsCreative Commons Attribution 3.0 Unportedcs
dc.rights.accessopenAccesscs
dc.rights.sherpahttp://www.sherpa.ac.uk/romeo/issn/1424-8220/cs
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/cs
dc.subjectflavonoidsen
dc.subjectantioxidanten
dc.subjectcarbon paste electrodeen
dc.subjectsquare wave voltammetryen
dc.subjectwestern blot analysisen
dc.subjectcytochrome P450en
dc.subjectcanceren
dc.titleUtilizing of square wave voltammetry to detect flavonoids in the presence of human urineen
dc.type.driverarticleen
dc.type.statusPeer-revieweden
dc.type.versionpublishedVersionen
sync.item.dbidVAV-49680en
sync.item.dbtypeVAVen
sync.item.insts2020.03.30 16:57:59en
sync.item.modts2020.03.30 15:50:41en
thesis.grantorVysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií. Ústav mikroelektronikycs
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