A minireview on the bioinformatics analysis of mobile gene elements in microbiome research

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dc.contributor.authorSchwarzerová, Janacs
dc.contributor.authorLabanava, Anastasiyacs
dc.contributor.authorRychlík, Ivancs
dc.contributor.authorVarga, Margaretcs
dc.contributor.authorČejková, Darinacs
dc.coverage.issue1cs
dc.coverage.volume2cs
dc.date.issued2023-10-11cs
dc.description.abstractThe horizontal transfer of mobile gene elements between bacteria plays a crucial role in their evolutionary dynamics. Additionally, it enables the accumulation and dissemination of genes conferring antibiotic and heavy-metal resistance, and thus contributes to the worldwide emergence and spread of drug-resistance pathogens. This process is instrumental in maintaining genetic diversity within bacterial populations and facilitates their adaptation to novel environments. It allows bacteria to acquire genes responsible for the synthesis of enzymes that utilize alternative energy sources and substrates. Furthermore, bacteria can acquire genes associated with toxin production and increased virulence. Horizontal gene transfer serves as a pivotal mechanism in bacterial evolution, enabling the acquisition of novel genetic information and enhancing their capabilities. However, the proper detection and identification of horizontally transferred genes at the microbiome scale is challenging, whether using wet-lab experimeen
dc.formattextcs
dc.format.extent8cs
dc.format.mimetypeapplication/pdfcs
dc.identifier.citationFrontiers in Bacteriology. 2023, vol. 2, issue 1, 8 p.en
dc.identifier.doi10.3389/fbrio.2023.1275910cs
dc.identifier.issn2813-6144cs
dc.identifier.orcid0000-0003-2918-9313cs
dc.identifier.orcid0000-0002-6989-6330cs
dc.identifier.other185424cs
dc.identifier.scopus23099215700cs
dc.identifier.urihttp://hdl.handle.net/11012/245103
dc.language.isoencs
dc.publisherFrontierscs
dc.relation.ispartofFrontiers in Bacteriologycs
dc.relation.urihttps://www.frontiersin.org/articles/10.3389/fbrio.2023.1275910/fullcs
dc.rightsCreative Commons Attribution 4.0 Internationalcs
dc.rights.accessopenAccesscs
dc.rights.sherpahttp://www.sherpa.ac.uk/romeo/issn/2813-6144/cs
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/cs
dc.subjecthorizontal gene transferen
dc.subjectbacterial genomicsen
dc.subjectmobilomeen
dc.subjectmicrobiomeen
dc.subjectgenome analysisen
dc.titleA minireview on the bioinformatics analysis of mobile gene elements in microbiome researchen
dc.type.driverarticleen
dc.type.statusPeer-revieweden
dc.type.versionpublishedVersionen
sync.item.dbidVAV-185424en
sync.item.dbtypeVAVen
sync.item.insts2025.02.03 15:39:59en
sync.item.modts2025.01.17 16:53:14en
thesis.grantorVysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií. Ústav biomedicínského inženýrstvícs
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