A minireview on the bioinformatics analysis of mobile gene elements in microbiome research
Loading...
Date
2023-10-11
Authors
Schwarzerová, Jana
Labanava, Anastasiya
Rychlík, Ivan
Varga, Margaret
Čejková, Darina
0000-0003-2918-9313Advisor
Referee
Mark
Journal Title
Journal ISSN
Volume Title
Publisher
Frontiers
Altmetrics
Abstract
The horizontal transfer of mobile gene elements between bacteria plays a crucial role in their evolutionary dynamics. Additionally, it enables the accumulation and dissemination of genes conferring antibiotic and heavy-metal resistance, and thus contributes to the worldwide emergence and spread of drug-resistance pathogens. This process is instrumental in maintaining genetic diversity within bacterial populations and facilitates their adaptation to novel environments. It allows bacteria to acquire genes responsible for the synthesis of enzymes that utilize alternative energy sources and substrates. Furthermore, bacteria can acquire genes associated with toxin production and increased virulence. Horizontal gene transfer serves as a pivotal mechanism in bacterial evolution, enabling the acquisition of novel genetic information and enhancing their capabilities. However, the proper detection and identification of horizontally transferred genes at the microbiome scale is challenging, whether using wet-lab experime
Description
Citation
Frontiers in Bacteriology. 2023, vol. 2, issue 1, 8 p.
https://www.frontiersin.org/articles/10.3389/fbrio.2023.1275910/full
https://www.frontiersin.org/articles/10.3389/fbrio.2023.1275910/full
Document type
Peer-reviewed
Document version
Published version
Date of access to the full text
Language of document
en