Biotribology of Synovial Cartilage: A New Method for Visualization of Lubricating Film and Simultaneous Measurement of the Friction Coefficient

dc.contributor.authorČípek, Pavelcs
dc.contributor.authorVrbka, Martincs
dc.contributor.authorRebenda, Davidcs
dc.contributor.authorNečas, Davidcs
dc.contributor.authorKřupka, Ivancs
dc.coverage.issue9cs
dc.coverage.volume13cs
dc.date.issued2020-04-30cs
dc.description.abstractA healthy natural synovial joint is very important for painless active movement of the natural musculoskeletal system. The right functioning of natural synovial joints ensures well lubricated contact surfaces with a very low friction coefficient and wear of cartilage tissue. The present paper deals with a new method for visualization of lubricating film with simultaneous measurements of the friction coefficient. This can contribute to better understanding of lubricating film formation in a natural synovial joint. A newly developed device, a reciprocating tribometer, is used to allow for simultaneous measurement of friction forces with contact visualization by fluorescence microscopy. The software allowing for snaps processing and subsequent evaluation of fluorescence records is developed. The evaluation software and the follow-up evaluation procedure are also described. The experiments with cartilage samples and model synovial fluid are carried out, and the new software is applied to provide their evaluation. The primary results explaining a connection between lubrication and friction are presented. The results show a more significant impact of albumin proteins on the lubrication process, whereas its clusters create a more stable lubrication layer. A decreasing trend of protein cluster count, which corresponds to a decrease in the thickness of the lubrication film, is found in all experiments. The results highlight a deeper connection between the cartilage friction and the lubrication film formation, which allows for better understanding of the cartilage lubrication mechanism.en
dc.formattextcs
dc.format.extent1-20cs
dc.format.mimetypeapplication/pdfcs
dc.identifier.citationMaterials . 2020, vol. 13, issue 9, p. 1-20.en
dc.identifier.doi10.3390/ma13092075cs
dc.identifier.issn1996-1944cs
dc.identifier.orcid0000-0002-6556-1816cs
dc.identifier.orcid0000-0002-2845-3752cs
dc.identifier.orcid0000-0002-5407-1336cs
dc.identifier.orcid0000-0002-3843-8732cs
dc.identifier.orcid0000-0002-9936-7480cs
dc.identifier.other163869cs
dc.identifier.researcheridB-1777-2017cs
dc.identifier.researcheridF-5568-2012cs
dc.identifier.researcheridB-1770-2017cs
dc.identifier.researcheridI-7816-2014cs
dc.identifier.researcheridD-8147-2012cs
dc.identifier.scopus56635672600cs
dc.identifier.urihttp://hdl.handle.net/11012/187002
dc.language.isoencs
dc.publisherMDPIcs
dc.relation.ispartofMaterialscs
dc.relation.urihttps://www.mdpi.com/1996-1944/13/9/2075cs
dc.rightsCreative Commons Attribution 4.0 Internationalcs
dc.rights.accessopenAccesscs
dc.rights.sherpahttp://www.sherpa.ac.uk/romeo/issn/1996-1944/cs
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/cs
dc.subjectbiotribologyen
dc.subjectcartilageen
dc.subjectreciprocating tribometeren
dc.subjectfrictionen
dc.subjectlubricationen
dc.subjectfluorescence microscopyen
dc.subjectbiotribologie
dc.subjectchrupavka
dc.subjectreciproční tribomtr
dc.subjecttření
dc.subjectmazání
dc.subjectfluorescenční mikroskopie
dc.titleBiotribology of Synovial Cartilage: A New Method for Visualization of Lubricating Film and Simultaneous Measurement of the Friction Coefficienten
dc.title.alternativeBiotribologie kloubní chrupavky: Nová metoda pro vizualizaci mazacího filmu a současné měření součinitele třenícs
dc.type.driverarticleen
dc.type.statusPeer-revieweden
dc.type.versionpublishedVersionen
sync.item.dbidVAV-163869en
sync.item.dbtypeVAVen
sync.item.insts2025.02.03 15:48:35en
sync.item.modts2025.01.17 16:33:49en
thesis.grantorVysoké učení technické v Brně. Fakulta strojního inženýrství. Ústav konstruovánícs
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