Oleaginous Yeast Extracts and Their Possible Effects on Human Health.

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dc.contributor.authorVysoká, Mariecs
dc.contributor.authorSzotkowski, Martincs
dc.contributor.authorSlaninová, Evacs
dc.contributor.authorDzurická, Luciacs
dc.contributor.authorStrečanská, Paulínacs
dc.contributor.authorBlažková, Janacs
dc.contributor.authorMárová, Ivanacs
dc.coverage.issue2cs
dc.coverage.volume11cs
dc.date.issued2023-02-16cs
dc.description.abstractFour non-conventional oleaginous and pigmented yeast strains of Metschnikowia pulcherrima, Cystofilobasidium infirmominiatum, Phaffia rhodozyma, and Rhodotorula kratochvilovae were used in this study. Complex yeast extracts were prepared and tested for biological activity, safety, and effect on human health. In this paper, we measured the antioxidant activity and antimicrobial effect of yeast biomass as a whole and their extracts to compare the influence of carotenoids and other bioactive substances in the studied biomass. All yeast extracts exhibited a significant dose-dependent antimicrobial effect against both G+ and G- bacteria and had a strong antioxidant effect. No cytotoxicity in the mouse melanoma B16F1 cell line was found in concentrations up to 20% of rehydrated biomass in cell medium. All of the extracts were cytotoxic at a concentration of 5 mg of extract/g of dry biomass. All the pigmented yeast extracts showed some positive results for apoptosis of murine melanoma cell lines and are therefore strong candidates positively effect human health. Red yeast cell biomass is a prospective material with many attractive biological functions and can be used in the food industry, as a pharmaceutical material, or in the feed industry.en
dc.formattextcs
dc.format.extent1-13cs
dc.format.mimetypeapplication/pdfcs
dc.identifier.citationMicroorganisms. 2023, vol. 11, issue 2, p. 1-13.en
dc.identifier.doi10.3390/microorganisms11020492cs
dc.identifier.issn2076-2607cs
dc.identifier.orcid0000-0002-9297-0703cs
dc.identifier.orcid0000-0002-1808-8632cs
dc.identifier.orcid0000-0003-2682-1897cs
dc.identifier.orcid0000-0002-2095-1837cs
dc.identifier.other183470cs
dc.identifier.researcheridA-6897-2016cs
dc.identifier.scopus6603465110cs
dc.identifier.urihttp://hdl.handle.net/11012/213541
dc.language.isoencs
dc.publisherMDPIcs
dc.relation.ispartofMicroorganismscs
dc.relation.urihttps://www.mdpi.com/2076-2607/11/2/492cs
dc.rightsCreative Commons Attribution 4.0 Internationalcs
dc.rights.accessopenAccesscs
dc.rights.sherpahttp://www.sherpa.ac.uk/romeo/issn/2076-2607/cs
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/cs
dc.subjectoleaginous yeasten
dc.subjectpigmented yeastsen
dc.subjectbioactive compoundsen
dc.subjectantimicrobial effecten
dc.subjectcytotoxic effecten
dc.subjectapoptosisen
dc.titleOleaginous Yeast Extracts and Their Possible Effects on Human Health.en
dc.type.driverarticleen
dc.type.statusPeer-revieweden
dc.type.versionpublishedVersionen
sync.item.dbidVAV-183470en
sync.item.dbtypeVAVen
sync.item.insts2025.02.03 15:38:00en
sync.item.modts2025.01.17 15:28:44en
thesis.grantorVysoké učení technické v Brně. Fakulta chemická. Ústav chemie potravin a biotechnologiícs
thesis.grantorVysoké učení technické v Brně. Fakulta chemická. Centrum materiálového výzkumucs
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