Graphene oxide as a nanocarrier for biochemical molecules: Current understanding and trends

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dc.contributor.authorMukherjee, S.cs
dc.contributor.authorBytešníková, Zuzanacs
dc.contributor.authorAmirmansoor, Ashrafics
dc.contributor.authorAdam, Vojtěchcs
dc.contributor.authorRichtera, Lukášcs
dc.coverage.issue12cs
dc.coverage.volume8cs
dc.date.accessioned2021-01-27T11:56:28Z
dc.date.available2021-01-27T11:56:28Z
dc.date.issued2020-12-30cs
dc.description.abstractThe development of an advanced and efficient drug delivery system with significant improvement in its efficacy and enhanced therapeutic value is one of the critical challenges in modern medicinal biology. The integration of nanomaterial science with molecular and cellular biology has helped in the advancement and development of novel drug delivery nanocarrier systems with precision and decreased side effects. The design and synthesis of nanocarriers using graphene oxide (GO) have been rapidly growing over the past few years. Due to its remarkable physicochemical properties, GO has been extensively used in efforts to construct nanocarriers with high specificity, selectivity, and biocompatibility, and low cytotoxicity. The focus of this review is to summarize and address recent uses of GO-based nanocarriers and the improvements as efficient drug delivery systems. We briefly describe the concepts and challenges associated with nanocarrier systems followed by providing critical examples of GO-based delivery of drug molecules and genes. Finally, the review delivers brief conclusions on the current understanding and prospects of nanocarrier delivery systems.en
dc.formattextcs
dc.format.extent1-22cs
dc.format.mimetypeapplication/pdfcs
dc.identifier.citationProcesses. 2020, vol. 8, issue 12, p. 1-22.en
dc.identifier.doi10.3390/pr8121636cs
dc.identifier.issn2227-9717cs
dc.identifier.other168305cs
dc.identifier.urihttp://hdl.handle.net/11012/195919
dc.language.isoencs
dc.publisherMDPIcs
dc.relation.ispartofProcessescs
dc.relation.urihttps://www.mdpi.com/2227-9717/8/12/1636cs
dc.rightsCreative Commons Attribution 4.0 Internationalcs
dc.rights.accessopenAccesscs
dc.rights.sherpahttp://www.sherpa.ac.uk/romeo/issn/2227-9717/cs
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/cs
dc.subjectgraphene oxideen
dc.subjectgrapheneen
dc.subjectnanocarrieren
dc.subjectdrug deliveryen
dc.subjectnanomaterialsen
dc.subjectcancer drugen
dc.subjectgene deliveryen
dc.titleGraphene oxide as a nanocarrier for biochemical molecules: Current understanding and trendsen
dc.type.driverarticleen
dc.type.statusPeer-revieweden
dc.type.versionpublishedVersionen
sync.item.dbidVAV-168305en
sync.item.dbtypeVAVen
sync.item.insts2021.01.27 12:56:28en
sync.item.modts2021.01.27 12:15:43en
thesis.grantorVysoké učení technické v Brně. Středoevropský technologický institut VUT. Chytré nanonástrojecs
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