Flow Injection Analysis Coupled with Carbon Electrodes as the Tool for Analysis of Naphthoquinones with Respect to Their Content and Functions in Biological Samples
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Date
2006-10-01
Authors
Babula, Petr
Křížková, Soňa
Adam, Vojtěch
Hubálek, Jaromír
Kizek, René
0000-0001-8529-552XAdvisor
Referee
Mark
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Volume Title
Publisher
MDPI
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Abstract
Naphthoquinones are one of the groups of secondary metabolites widespread in nature, where they mostly appear as chromatic pigments. They embody broad-range of biological actions from phytotoxic to fungicidal. An anticancer effect of naphthoquinones stimulates an interest in determination and characterization of single derivatives of 1,2- and 1,4-quinones in biological samples. The main aim of this work was to suggest a technique suitable to determine lawsone, juglone and/or plumbagin in biological samples and to study of their influence on BY-2 tobacco cells.
Naphthoquinones are one of the groups of secondary metabolites widespread in nature, where they mostly appear as chromatic pigments. They embody broad-range of biological actions from phytotoxic to fungicidal. An anticancer effect of naphthoquinones stimulates an interest in determination and characterization of single derivatives of 1,2- and 1,4-quinones in biological samples. The main aim of this work was to suggest a technique suitable to determine lawsone, juglone and/or plumbagin in biological samples and to study of their influence on BY-2 tobacco cells.
Naphthoquinones are one of the groups of secondary metabolites widespread in nature, where they mostly appear as chromatic pigments. They embody broad-range of biological actions from phytotoxic to fungicidal. An anticancer effect of naphthoquinones stimulates an interest in determination and characterization of single derivatives of 1,2- and 1,4-quinones in biological samples. The main aim of this work was to suggest a technique suitable to determine lawsone, juglone and/or plumbagin in biological samples and to study of their influence on BY-2 tobacco cells.
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Keywords
Naphthoquinones, Plumbagin, Lawsone, Juglone, BY-2 tobacco cells (Nicotiana tabaccum), Persian walnut (Juglans regia), Sensors, Flow analysis, Differential pulse voltammetry, Electrochemical detection, Carbon electrodes., Naphthoquinones, Plumbagin, Lawsone, Juglone, BY-2 tobacco cells (Nicotiana tabaccum), Persian walnut (Juglans regia), Sensors, Flow analysis, Differential pulse voltammetry, Electrochemical detection, Carbon electrodes.
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Peer-reviewed
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en