Flow Injection Analysis Coupled with Carbon Electrodes as the Tool for Analysis of Naphthoquinones with Respect to Their Content and Functions in Biological Samples

Babula, Petr; Křížková, Soňa; Adam, Vojtěch; Hubálek, Jaromír; Kizek, René

Flow Injection Analysis Coupled with Carbon Electrodes as the Tool for Analysis of Naphthoquinones with Respect to Their Content and Functions in Biological Samples

Files

sensors0601466.pdf(144.86 KB)

Date

2006-10-01

Authors

Babula, Petr

Křížková, Soňa

Adam, Vojtěch

Hubálek, Jaromír

Kizek, René

ORCID

Publisher

MDPI

Altmetrics

Abstract

Naphthoquinones are one of the groups of secondary metabolites widespread in nature, where they mostly appear as chromatic pigments. They embody broad-range of biological actions from phytotoxic to fungicidal. An anticancer effect of naphthoquinones stimulates an interest in determination and characterization of single derivatives of 1,2- and 1,4-quinones in biological samples. The main aim of this work was to suggest a technique suitable to determine lawsone, juglone and/or plumbagin in biological samples and to study of their influence on BY-2 tobacco cells.

Keywords

Naphthoquinones, Plumbagin, Lawsone, Juglone, BY-2 tobacco cells (Nicotiana tabaccum), Persian walnut (Juglans regia), Sensors, Flow analysis, Differential pulse voltammetry, Electrochemical detection, Carbon electrodes.

Citation

SENSORS. 2006, vol. 2006, issue 6, p. 1466-1482.
http://www.mdpi.com/1424-8220/6/11/1466

Document type

Peer-reviewed

Document version

Published version

Language of document

en