Mitochondria morphology and membrane potential under stress conditions

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but.event.date26.04.2022cs
but.event.titleSTUDENT EEICT 2022cs
dc.contributor.authorEzati, Masoumeh
dc.contributor.authorZumberg, Inna
dc.contributor.authorCmiel, Vratislav
dc.date.accessioned2023-04-25T10:17:10Z
dc.date.available2023-04-25T10:17:10Z
dc.date.issued2022cs
dc.description.abstractMitochondria, organelles found in the cytoplasm of almost all eukaryotic cells, generate large quantities of energy in the form of adenosine triphosphate (ATP). In addition to producing energy, mitochondria store calcium for cell signaling activities and play an important role in maintenance of ionic balance. Mitochondria, however, are highly sensitive to any kind of stress in which they mainly response by disturbance of respiration, reactive oxygen species (ROS) production and release of cytochrome c into the cytoplasm. Osmotic stress, in particular, generates ROS that degrade lipids, proteins, and DNA. High levels of salt concentration can cause an imbalance in cellular ion homeostasis that results in ion toxicity and osmotic stress. This study aims to investigate possible effects of KCl and NaCl on Bone marrow-derived (MSCs) mitochondria membrane potential (MMP) and morphology. The results indicated that KCl and NaCl of salt concentration can cause an imbalance in cellular ion homeostasis that results in ion toxicity and osmotic stress. This study aims to investigate possible effects of KCl and NaCl on MSCs mitochondria membrane potential (MMP) and morphology. The results indicated that KCl and NaCl decreased the potential and changed the morphology of mitochondria membrane compared to cells growing in normal condition.en
dc.formattextcs
dc.format.extent432-436cs
dc.format.mimetypeapplication/pdfen
dc.identifier.citationProceedings I of the 28st Conference STUDENT EEICT 2022: General papers. s. 432-436. ISBN 978-80-214-6029-4cs
dc.identifier.isbn978-80-214-6029-4
dc.identifier.urihttp://hdl.handle.net/11012/209380
dc.language.isoencs
dc.publisherVysoké učení technické v Brně, Fakulta elektrotechniky a komunikačních technologiícs
dc.relation.ispartofProceedings I of the 28st Conference STUDENT EEICT 2022: General papersen
dc.relation.urihttps://conf.feec.vutbr.cz/eeict/index/pages/view/ke_stazenics
dc.rights© Vysoké učení technické v Brně, Fakulta elektrotechniky a komunikačních technologiícs
dc.rights.accessopenAccessen
dc.subjectMitochondria membrane potentialen
dc.subjectMitochondria morphologyen
dc.subjectOsmotic stressen
dc.subjectMitochondria fusionen
dc.titleMitochondria morphology and membrane potential under stress conditionsen
dc.type.driverconferenceObjecten
dc.type.statusPeer-revieweden
dc.type.versionpublishedVersionen
eprints.affiliatedInstitution.departmentFakulta elektrotechniky a komunikačních technologiícs
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