An Investigation on the Electrochemical Behavior and Antibacterial and Cytotoxic Activity of Nickel Trithiocyanurate Complexes

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dc.contributor.authorAshrafi, Amirmansoorcs
dc.contributor.authorKopel, Pavelcs
dc.contributor.authorRichtera, Lukášcs
dc.coverage.issue7cs
dc.coverage.volume13cs
dc.date.issued2020-04-10cs
dc.description.abstractThe electrochemical redox behavior of three trinuclear Ni(II) complexes [Ni3(abb)3(H2O)3(µ-ttc)](ClO4)3 (1), [Ni3(tebb)3(H2O)3(µ-ttc)](ClO4)3·H2O (2), and [Ni3(pmdien)3(µ-ttc)](ClO4)3 (3), where abb = 1-(1H-benzimidazol-2-yl)-N-(1H-benzimidazol-2-ylmethyl)methan-amine, ttcH3 = trithiocyanuric acid, tebb = 2-[2-[2-(1H-benzimidazol-2-yl)ethylsulfanyl]ethyl]-1H-benzimidazole, and pmdien = N,N,N,N,N-pentamethyldiethylenetriamine is reported. Cyclic voltammetry (CV) was applied for the study of the electrochemical behavior of these compounds. The results confirmed the presence of ttc and nickel in oxidation state +2 in the synthesized complexes. Moreover, the antibacterial properties and cytotoxic activity of complex 3 was investigated. All the complexes show antibacterial activity against Staphylococcus aureus and Escherichia coli to different extents. The cytotoxic activity of complex 3 and ttcNa3 were studied on G-361, HOS, K-562, and MCF7 cancer cell lines. It was found out that complex 3 possesses the cytotoxic activity against the tested cell lines, whereas ttcNa3 did not show any cytotoxic activity.en
dc.formattextcs
dc.format.extent1-8cs
dc.format.mimetypeapplication/pdfcs
dc.identifier.citationMaterials . 2020, vol. 13, issue 7, p. 1-8.en
dc.identifier.doi10.3390/ma13071782cs
dc.identifier.issn1996-1944cs
dc.identifier.orcid0000-0003-4216-9544cs
dc.identifier.orcid0000-0002-8288-3999cs
dc.identifier.other163533cs
dc.identifier.researcheridE-5711-2012cs
dc.identifier.researcheridN-9991-2014cs
dc.identifier.scopus6603604023cs
dc.identifier.scopus12040049600cs
dc.identifier.urihttp://hdl.handle.net/11012/186820
dc.language.isoencs
dc.publisherMDPIcs
dc.relation.ispartofMaterialscs
dc.relation.urihttps://www.mdpi.com/1996-1944/13/7/1782/htmcs
dc.rightsCreative Commons Attribution 4.0 Internationalcs
dc.rights.accessopenAccesscs
dc.rights.sherpahttp://www.sherpa.ac.uk/romeo/issn/1996-1944/cs
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/cs
dc.subjectnickel complexesen
dc.subjecttrithiocyanuric aciden
dc.subjecttrimercaptotriazineen
dc.subjectcyclic voltammetryen
dc.titleAn Investigation on the Electrochemical Behavior and Antibacterial and Cytotoxic Activity of Nickel Trithiocyanurate Complexesen
dc.type.driverarticleen
dc.type.statusPeer-revieweden
dc.type.versionpublishedVersionen
sync.item.dbidVAV-163533en
sync.item.dbtypeVAVen
sync.item.insts2025.02.03 15:40:54en
sync.item.modts2025.01.17 19:34:51en
thesis.grantorVysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií. Ústav mikroelektronikycs
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