Finite element analysis of 6 large PMMA skull reconstructions: A multi-criteria evaluation approach

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dc.contributor.authorRidwan-Pramana, Angelacs
dc.contributor.authorMarcián, Petrcs
dc.contributor.authorBorák, Liborcs
dc.contributor.authorNarra, Nathanielcs
dc.contributor.authorForouzanfar, Timcs
dc.contributor.authorWolff, Jancs
dc.coverage.issue6cs
dc.coverage.volume12cs
dc.date.issued2017-06-13cs
dc.description.abstractIn this study 6 pre-operative designs for PMMA based reconstructions of cranial defects were evaluated for their mechanical robustness using finite element modeling. Clinical experience and engineering principles were employed to create multiple plan options, which were subsequently computationally analyzed for mechanically relevant parameters under 50N loads: stress, strain and deformation in various components of the assembly. The factors assessed were: defect size, location and shape. The major variable in the cranioplasty assembly design was the arrangement of the fixation plates. An additional study variable introduced was the location of the 50N load within the implant area. It was found that in smaller defects, it was simpler to design a symmetric distribution of plates and under limited variability in load location it was possible to design an optimal for expected loads. However, for very large defects with complex shapes, the variability in the load locations introduces complications to the intuitive design of the optimal assembly. The study shows that it can be beneficial to incorporate multi design computational analyses to decide upon the most optimal plan for a clinical case.en
dc.description.abstractIn this study 6 pre-operative designs for PMMA based reconstructions of cranial defects were evaluated for their mechanical robustness using finite element modeling. Clinical experience and engineering principles were employed to create multiple plan options, which were subsequently computationally analyzed for mechanically relevant parameters under 50N loads: stress, strain and deformation in various components of the assembly. The factors assessed were: defect size, location and shape. The major variable in the cranioplasty assembly design was the arrangement of the fixation plates. An additional study variable introduced was the location of the 50N load within the implant area. It was found that in smaller defects, it was simpler to design a symmetric distribution of plates and under limited variability in load location it was possible to design an optimal for expected loads. However, for very large defects with complex shapes, the variability in the load locations introduces complications to the intuitive design of the optimal assembly. The study shows that it can be beneficial to incorporate multi design computational analyses to decide upon the most optimal plan for a clinical case.en
dc.formattextcs
dc.format.extent1-16cs
dc.format.mimetypeapplication/pdfcs
dc.identifier.citationPLoS One. 2017, vol. 12, issue 6, p. 1-16.en
dc.identifier.doi10.1371/journal.pone.0179325cs
dc.identifier.issn1932-6203cs
dc.identifier.orcid0000-0002-9458-9690cs
dc.identifier.orcid0000-0001-9785-0578cs
dc.identifier.other137080cs
dc.identifier.researcheridE-7359-2017cs
dc.identifier.researcheridCIK-1174-2022cs
dc.identifier.scopus55156647700cs
dc.identifier.scopus46661854700cs
dc.identifier.urihttp://hdl.handle.net/11012/193256
dc.language.isoencs
dc.publisherPLOScs
dc.relation.ispartofPLoS Onecs
dc.relation.urihttps://journals.plos.org/plosone/article?id=10.1371/journal.pone.0179325cs
dc.rightsCreative Commons Attribution 4.0 Internationalcs
dc.rights.accessopenAccesscs
dc.rights.sherpahttp://www.sherpa.ac.uk/romeo/issn/1932-6203/cs
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/cs
dc.subjectCranioplastyen
dc.subjectFEMen
dc.subjectPMMAen
dc.subjectCranial implanten
dc.subjectMechanical propertiesen
dc.subjectplate distributionen
dc.subjectfixation geometryen
dc.subjectCranioplasty
dc.subjectFEM
dc.subjectPMMA
dc.subjectCranial implant
dc.subjectMechanical properties
dc.subjectplate distribution
dc.subjectfixation geometry
dc.titleFinite element analysis of 6 large PMMA skull reconstructions: A multi-criteria evaluation approachen
dc.title.alternativeFinite element analysis of 6 large PMMA skull reconstructions: A multi-criteria evaluation approachen
dc.type.driverarticleen
dc.type.statusPeer-revieweden
dc.type.versionpublishedVersionen
sync.item.dbidVAV-137080en
sync.item.dbtypeVAVen
sync.item.insts2025.10.14 15:07:20en
sync.item.modts2025.10.14 10:03:35en
thesis.grantorVysoké učení technické v Brně. Fakulta strojního inženýrství. Ústav mechaniky těles, mechatroniky a biomechanikycs
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