Synthesis, characterization and In-vitro studies of CNT/Gd 2 O 3 hybrid structure
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Date
2023-06-01
Authors
Paul, Rima
Chatterjee, Dipanwita
Das Ghosh, Lopamudra
Narayanswamy, Venkatesha
Pratap Singh, Mahander
Agarwal, Manish
Ghosh, Deepshikha
Radhakrishna, Mithun
Sekhar Tiwary, Chandra
Provazník, Valentýna
0000-0003-4930-0496Advisor
Referee
Mark
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Elsevier
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Abstract
Carbon nanotubes have been explored in various fields of science and technology due to their unique properties. However, their toxic nature put limitations to its consideration for the bio-medical applications. In our work, we report the synthesis of paramagnetic CNT/Gd 2 O 3 hybrid nanostructures through easily scalable electrochemical deposition technique. The nanostructure has shown significant longitudinal relaxivity of 18.93 mM 1 s 1 for water protons indicating its possibility to be used as an MRI contrast agent. The in-vitro cytotoxicity test on the normal (HaCaT) and cancerous (HeLa) cells reveal that CNT/Gd 2 O 3 hybrid nanostructure is bio-compatible in comparison to the pure CNTs, which is further supported by our theoretical studies using MD simulations.
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Peer-reviewed
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en