Identification of horizontal genes transfer elements across strains inhabiting the same niche using pan-genome analysis

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but.event.date26.04.2022cs
but.event.titleSTUDENT EEICT 2022cs
dc.contributor.authorSchwarzerová, J.
dc.contributor.authorČejková, D.
dc.date.accessioned2023-04-25T10:17:10Z
dc.date.available2023-04-25T10:17:10Z
dc.date.issued2022cs
dc.description.abstractTracing horizontal gene flux across strains in farm animals is one of the important steps for research focused on detection and genomic enzymology of genes conferring antibiotic resistance. In this study, we have built the comprehensive computational methodology for the detection of horizontal genes transfer elements via pan-genome analysis. In total, 133 anaerobes isolated from chicken gastrointestinal tract were examined for the presence of traits of horizontal transfer. The shared genes from all isolates, so called core genome genes were identified and characterised in order to assign the function to the gene within individual bacterial cell and within community of cells. This study provides an evidence that horizontal transmission frequently occurs not only between closely related bacteria, but also between distant taxonomical groups. Hence chickens are known primary reservoirs of antibiotic resistance genes, and the dissemination of these genes to other bacterial pathogens often leads to life-threatening infections, even within human population. Thus, the research on this subject, and the associated results are of a great importance for public health.en
dc.formattextcs
dc.format.extent416-420cs
dc.format.mimetypeapplication/pdfen
dc.identifier.citationProceedings I of the 28st Conference STUDENT EEICT 2022: General papers. s. 416-420. ISBN 978-80-214-6029-4cs
dc.identifier.isbn978-80-214-6029-4
dc.identifier.urihttp://hdl.handle.net/11012/209377
dc.language.isoencs
dc.publisherVysoké učení technické v Brně, Fakulta elektrotechniky a komunikačních technologiícs
dc.relation.ispartofProceedings I of the 28st Conference STUDENT EEICT 2022: General papersen
dc.relation.urihttps://conf.feec.vutbr.cz/eeict/index/pages/view/ke_stazenics
dc.rights© Vysoké učení technické v Brně, Fakulta elektrotechniky a komunikačních technologiícs
dc.rights.accessopenAccessen
dc.subjectComparative Genomicsen
dc.subjectCore Genomeen
dc.subjectAntibiotics Resistanceen
dc.subjectChicken Microbiomeen
dc.titleIdentification of horizontal genes transfer elements across strains inhabiting the same niche using pan-genome analysisen
dc.type.driverconferenceObjecten
dc.type.statusPeer-revieweden
dc.type.versionpublishedVersionen
eprints.affiliatedInstitution.departmentFakulta elektrotechniky a komunikačních technologiícs
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