2D graphene-based advanced nanoarchitectonics for electrochemical biosensors: Applications in cancer biomarker detection

Simple item page
dc.contributor.authorMukherjee, Soumajitcs
dc.contributor.authorMukherjee, Atripancs
dc.contributor.authorBytešníková, Zuzanacs
dc.contributor.authorAshrafi, Amirmansoorcs
dc.contributor.authorRichtera, Lukášcs
dc.contributor.authorAdam, Vojtěchcs
dc.coverage.issueAprilcs
dc.coverage.volume250cs
dc.date.accessioned2025-06-17T07:58:32Z
dc.date.available2025-06-17T07:58:32Z
dc.date.issued2024-04-15cs
dc.description.abstractLow-cost, rapid, and easy-to-use biosensors for various cancer biomarkers are of utmost importance in detecting cancer biomarkers for early-stage metastasis control and efficient diagnosis. The molecular complexity of cancer biomarkers is overwhelming, thus, the repeatability and reproducibility of measurements by biosensors are critical factors. Electrochemical biosensors are attractive alternatives in cancer diagnosis due to their low cost, simple operation, and promising analytical figures of merit. Recently graphene-derived nanostructures have been used extensively for the fabrication of electrochemical biosensors because of their unique physicochemical properties, including the high electrical conductivity, adsorption capacity, low cost and ease of mass production, presence of oxygen-containing functional groups that facilitate the bioreceptor immobilization, increased flexibility and mechanical strength, low cellular toxicity. Indeed, these properties make them advantageous compared to other alternatives. However, some drawbacks must be overcome to extend their use, such as poor and uncontrollable deposition on the substrate due to the low dispersity of some graphene materials and irreproducibility of the results because of the differences in various batches of the produced graphene materials. This review has documented the most recently developed strategies for electrochemical sensor fabrication. It differs in the categorization method compared to published works to draw greater attention to the wide opportunities of graphene nanomaterials for biological applications. Limitations and future scopes are discussed to advance the integration of novel technologies such as artificial intelligence, the internet of medical things, and triboelectric nanogenerators to eventually increase efficacy and efficiency.en
dc.formattextcs
dc.format.extent1-19cs
dc.format.mimetypeapplication/pdfcs
dc.identifier.citationBIOSENSORS & BIOELECTRONICS. 2024, vol. 250, issue April, p. 1-19.en
dc.identifier.doi10.1016/j.bios.2024.116050cs
dc.identifier.issn1873-4235cs
dc.identifier.orcid0000-0002-8288-3999cs
dc.identifier.orcid0000-0002-8527-286Xcs
dc.identifier.other188937cs
dc.identifier.researcheridN-9991-2014cs
dc.identifier.researcheridD-7686-2012cs
dc.identifier.scopus12040049600cs
dc.identifier.urihttps://hdl.handle.net/11012/252861
dc.language.isoencs
dc.publisherELSEVIER ADVANCED TECHNOLOGYcs
dc.relation.ispartofBIOSENSORS & BIOELECTRONICScs
dc.relation.urihttps://www.sciencedirect.com/science/article/pii/S0956566324000538cs
dc.rightsCreative Commons Attribution 4.0 Internationalcs
dc.rights.accessopenAccesscs
dc.rights.sherpahttp://www.sherpa.ac.uk/romeo/issn/1873-4235/cs
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/cs
dc.subject2D nanocompositesen
dc.subjectSensor developmenten
dc.subjectElectrochemical biosensoren
dc.subjectCancer biomarkeren
dc.subjectGrapheneen
dc.title2D graphene-based advanced nanoarchitectonics for electrochemical biosensors: Applications in cancer biomarker detectionen
dc.type.driverarticleen
dc.type.statusPeer-revieweden
dc.type.versionpublishedVersionen
sync.item.dbidVAV-188937en
sync.item.dbtypeVAVen
sync.item.insts2025.06.17 09:58:32en
sync.item.modts2025.06.17 09:33:21en
thesis.grantorVysoké učení technické v Brně. Středoevropský technologický institut VUT. Laserová spektroskopiecs
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
1s2.0S0956566324000538main.pdf
Size:
7.97 MB
Format:
Adobe Portable Document Format
Description:
file 1s2.0S0956566324000538main.pdf
Download
Collections
Laserová spektroskopie