The Overlooked Fact: the Critical Role of Bioinformatics Pipeline in Microbiome Analysis

Simple item page
but.event.date23.04.2024cs
but.event.titleSTUDENT EEICT 2024cs
dc.contributor.authorPolakovičová, Petra
dc.date.accessioned2024-07-09T07:38:36Z
dc.date.available2024-07-09T07:38:36Z
dc.date.issued2024cs
dc.description.abstractThe research on the human microbiome has gained significant popularity over the past couple of years across both scientific and public communities. This area has revealed considerable knowledge, mainly thanks to next-generation sequencing. Even though technology possibilities evolve faster than ever, and there is an enormous amount of publicly available data, there are not yet precise procedures, methods, and bioinformatics tools to work accurately enough with microbiome data, and there are no standardized recommendations for bioinformatics pipelines to assess the most accurate results. Here, we demonstrate the potential inaccuracies that can arise from various bioinformatics processing of amplicon 16S RNA sequencing data by performing a comparative analysis of diverse pipeline configurations using mock community samples and biological material originating from biopsy samples obtained during regular colonoscopy from patients with primary sclerosing cholangitis.en
dc.formattextcs
dc.format.extent101-104cs
dc.format.mimetypeapplication/pdfen
dc.identifier.citationProceedings I of the 30st Conference STUDENT EEICT 2024: General papers. s. 101-104. ISBN 978-80-214-6231-1cs
dc.identifier.isbn978-80-214-6231-1
dc.identifier.urihttps://hdl.handle.net/11012/249206
dc.language.isoencs
dc.publisherVysoké učení technické v Brně, Fakulta elektrotechniky a komunikačních technologiícs
dc.relation.ispartofProceedings I of the 30st Conference STUDENT EEICT 2024: General papersen
dc.relation.urihttps://www.eeict.cz/eeict_download/archiv/sborniky/EEICT_2024_sbornik_1.pdfcs
dc.rights© Vysoké učení technické v Brně, Fakulta elektrotechniky a komunikačních technologiícs
dc.rights.accessopenAccessen
dc.subjectmicrobiomeen
dc.subjectbioinformaticsen
dc.subjectcomparative analysisen
dc.subject16S rRNAen
dc.titleThe Overlooked Fact: the Critical Role of Bioinformatics Pipeline in Microbiome Analysisen
dc.type.driverconferenceObjecten
dc.type.statusPeer-revieweden
dc.type.versionpublishedVersionen
eprints.affiliatedInstitution.departmentFakulta elektrotechniky a komunikačních technologiícs
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
101-eeict-2024.pdf
Size:
534.77 KB
Format:
Adobe Portable Document Format
Description:
Download
Collections
Student EEICT 2024: General Papers