Comparison of the Resistance to Bending Forces of the 4.5 LCP Plate-rod Construct and of 4.5 LCP Alone Applied to Segmental Femoral Defects in Miniature Pigs

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dc.contributor.authorUrbanová, Luciecs
dc.contributor.authorSrnec, Robertcs
dc.contributor.authorProks, Pavelcs
dc.contributor.authorStehlík, Ladislavcs
dc.contributor.authorFlorian, Zdeněkcs
dc.contributor.authorNávrat, Tomášcs
dc.contributor.authorNečas, Aloiscs
dc.coverage.issue4cs
dc.coverage.volume79cs
dc.date.accessioned2019-04-03T03:54:32Z
dc.date.available2019-04-03T03:54:32Z
dc.date.issued2010-12-20cs
dc.description.abstractThe study deals with the determination of mechanical properties, namely resistance to bending forces, of flexible buttress osteosynthesis using two different bone-implant constructs stabilizing experimental segmental femoral bone defects (segmental ostectomy) in a miniature pig ex vivo model using 4.5 mm titanium LCP and a 3 mm intramedullary pin ("plate and rod" construct) (PR-LCP), versus the 4.5 mm titanium LCP alone (A-LCP). The "plate and rod" fixation (PR-LCP) of the segmental femoral defect is significantly more resistant (p < 0.05) to bending forces (200 N, 300 N, and 500 N) than LCP alone (A-LCP). Stabilisation of experimental segmental lesions of the femoral diaphysis in miniature pigs by flexible bridging osteosynthesis 4.5 mm LCP in combination with the "plate and rod" construct appears to be a suitable fixation of non-reducible fractures where considerable strain of the implants by bending forces can be assumed. These findings will be used in upcoming in vivo experiments in the miniature pig to investigate bone defect healing after transplantation of mesenchymal stem cells in combination with biocompatible scaffolds.en
dc.description.abstractStudie se zabývá stanovením mechanických vlastností, zejména odolnost vůči ohybu, pružné opěrné osteosyntézy s použitím dvou různých kostních implantátů (4.5 mm titanium LCP a 3 mm drát, 4.5 mm titanium LCP bez drátu). Implantát stabilizuje porušenou stehenní kost.cs
dc.formattextcs
dc.format.extent613-620cs
dc.format.mimetypeapplication/pdfcs
dc.identifier.citationACTA VETERINARIA BRNO. 2010, vol. 79, issue 4, p. 613-620.en
dc.identifier.doi10.2754/avb201079040613cs
dc.identifier.issn0001-7213cs
dc.identifier.other43431cs
dc.identifier.urihttp://hdl.handle.net/11012/137199
dc.language.isoencs
dc.publisherUniversity of Veterinary and Pharmaceutical Sciences in Brnocs
dc.relation.ispartofACTA VETERINARIA BRNOcs
dc.relation.urihttps://actavet.vfu.cz/79/4/0613/cs
dc.rightsCreative Commons Attribution 4.0 Internationalcs
dc.rights.accessopenAccesscs
dc.rights.sherpahttp://www.sherpa.ac.uk/romeo/issn/0001-7213/cs
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/cs
dc.subjectFracture fixationen
dc.subjectcomminuted fractureen
dc.subjectostectomyen
dc.subjectbuttress osteosynthesisen
dc.subjectimplant failureen
dc.subjectFixaci zlomeniny
dc.subjecttříštivá zlomenina
dc.subjectostectomie
dc.subjectosteosyntéza
dc.subjectporušení implantátu
dc.titleComparison of the Resistance to Bending Forces of the 4.5 LCP Plate-rod Construct and of 4.5 LCP Alone Applied to Segmental Femoral Defects in Miniature Pigsen
dc.title.alternativeSrovnácí studie odolnost vůči ohybu dlahy 4.5 LCP Plate-rod Construct tyč a 4.5 LCP Alone aplikované na porušený femur prasetecs
dc.type.driverarticleen
dc.type.statusPeer-revieweden
dc.type.versionpublishedVersionen
sync.item.dbidVAV-43431en
sync.item.dbtypeVAVen
sync.item.insts2020.03.31 00:59:16en
sync.item.modts2020.03.30 22:58:33en
thesis.grantorVysoké učení technické v Brně. Fakulta strojního inženýrství. Ústav mechaniky těles, mechatroniky a biomechanikycs
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