Biotechnological production of polyhydroxyalkanoates from glycerol: A review
Loading...
Date
2022-07-01
Authors
Koller, Martin
Obruča, Stanislav
ORCID
0000-0002-9270-195XAdvisor
Referee
Mark
Journal Title
Journal ISSN
Volume Title
Publisher
Elsevier
Altmetrics
Abstract
Current worldwide threats related to global warming, climate change, and depletion of limited fossil resources necessitate the switch of industry towards producing carbon-neutral chemicals, solvents, fuels, and plastics. In this context, biotechnology offers alternatives to established plastics from petrochemistry, namely microbial polyhydroxyalkanoate (PHA) biopolyesters. PHA, circular in their nature, span a broad range of material properties, which can be finetuned by the biotechnological production strategy; this way, PHA can mimic both thermoplastics and elastomers from petrochemistry. However, it's the still high production costs that impede the ultimate market penetration of PHA to replace established recalcitrant types of plastics. Selecting inexpensive waste and surplus materials from diverse industrial sectors for being used as biotechnological feedstocks for the production of PHA is among the most auspicious steps to increase PHA's competitiveness with petrochemical plastics. In this context, glycerol, an abundant carbonaceous side stream from steadily increasing biodiesel production, is among the globally emerging inexpensive materials for this purpose. The review article at hand provides an overview of how the renewable, high-volume, low-value resource glycerol can be converted by most diverse prokaryotic production strains to PHA of different structure and properties and highlights obstacles and particular benefits when using this waste stream for biopolyesters synthesis, with special emphasis dedicated to most recent developments, and the application of naturally occurring organisms (wild type strains) isolated from most diverse habitats.
Description
Citation
Biocatalysis and Agricultural Biotechnology. 2022, vol. 42, issue 6, p. 1-31.
https://www.sciencedirect.com/science/article/pii/S1878818122000603
https://www.sciencedirect.com/science/article/pii/S1878818122000603
Document type
Peer-reviewed
Document version
Published version
Date of access to the full text
Language of document
en