Compact Monocular Video-Ophthalmoscope to Measure Retinal Reflectance Changes to Flicker Light Stimuli

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dc.contributor.authorKolář, Radimcs
dc.contributor.authorVičar, Tomášcs
dc.contributor.authorChmelík, Jiřícs
dc.contributor.authorJakubíček, Romancs
dc.contributor.authorOdstrčilík, Jancs
dc.contributor.authorNohel, Michalcs
dc.contributor.authorSkorkovská, Karolínacs
dc.contributor.authorTornow, Ralf-Petercs
dc.coverage.issue6cs
dc.coverage.volume18cs
dc.date.accessioned2025-08-21T12:56:57Z
dc.date.available2025-08-21T12:56:57Z
dc.date.issued2025-03-11cs
dc.description.abstractThis paper describes a compact video-ophthalmoscope (VO) designed for capturing retinal video sequences of the optic nerve head (ONH) under flicker light stimulation. The device uses an OLED display and a fiber optic-coupled LED light source, enabling high-frame-rate video at low illumination intensity (12 mu W/cm2). Retinal responses were recorded in 10 healthy subjects during flicker light exposure with a pupil irradiance of 2 mu W/cm2. Following 20 s of stimulation, all subjects displayed changes in retinal reflectance and pulsation attenuation, linked to blood flow and volume variations. These findings suggest that increased blood volume leads to decreased retinal reflectance. Temporal analysis confirmed the ability to capture flicker-induced retinal reflectance changes, indicating its potential for spatial and temporal analysis. Overall, this device offers a portable approach for investigating dynamic retinal responses to light stimuli, which can aid the diagnosis of retinal diseases like diabetic retinopathy, glaucoma, or neurodegenerative diseases affecting retinal blood circulation.en
dc.formattextcs
dc.format.extent10cs
dc.format.mimetypeapplication/pdfcs
dc.identifier.citationJournal of Biophotonics. 2025, vol. 18, issue 6, 10 p.en
dc.identifier.doi10.1002/jbio.202400494cs
dc.identifier.issn1864-0648cs
dc.identifier.orcid0000-0002-0469-6397cs
dc.identifier.orcid0000-0002-9136-7873cs
dc.identifier.orcid0000-0001-9950-6279cs
dc.identifier.orcid0000-0003-4293-260Xcs
dc.identifier.orcid0000-0001-7053-6183cs
dc.identifier.orcid0000-0002-2679-2160cs
dc.identifier.other197697cs
dc.identifier.researcheridC-8547-2014cs
dc.identifier.researcheridC-6006-2018cs
dc.identifier.researcheridH-9359-2017cs
dc.identifier.researcheridD-3622-2018cs
dc.identifier.researcheridA-2237-2016cs
dc.identifier.researcheridGQJ-8442-2022cs
dc.identifier.scopus57202426072cs
dc.identifier.scopus57188877911cs
dc.identifier.scopus35753651000cs
dc.identifier.scopus57222009745cs
dc.identifier.urihttps://hdl.handle.net/11012/255462
dc.language.isoencs
dc.publisherWILEY-V C H VERLAG GMBHcs
dc.relation.ispartofJournal of Biophotonicscs
dc.relation.urihttps://onlinelibrary.wiley.com/doi/10.1002/jbio.202400494cs
dc.rightsCreative Commons Attribution-NonCommercial 4.0 Internationalcs
dc.rights.accessopenAccesscs
dc.rights.sherpahttp://www.sherpa.ac.uk/romeo/issn/1864-0648/cs
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/cs
dc.subjectblood volumeen
dc.subjectfundus reflectanceen
dc.subjectlight flickeringen
dc.subjectneurovascular couplingen
dc.subjectoptic nerve headen
dc.subjectvideo-ophthalmoscopyen
dc.titleCompact Monocular Video-Ophthalmoscope to Measure Retinal Reflectance Changes to Flicker Light Stimulien
dc.type.driverarticleen
dc.type.statusPeer-revieweden
dc.type.versionpublishedVersionen
sync.item.dbidVAV-197697en
sync.item.dbtypeVAVen
sync.item.insts2025.08.21 14:56:57en
sync.item.modts2025.08.21 14:34:21en
thesis.grantorVysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií. Ústav biomedicínského inženýrstvícs
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