BacSeqer: Read simulator for bacterial RNA-Seq

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but.event.date23.04.2024cs
but.event.titleSTUDENT EEICT 2024cs
dc.contributor.authorFialová, Adéla
dc.contributor.authorSedlář, Karel
dc.date.accessioned2024-07-09T07:47:49Z
dc.date.available2024-07-09T07:47:49Z
dc.date.issued2024cs
dc.description.abstractThe RNA-Seq method has become a key tool in transcriptomics, providing deep insight into the genetic functioning of organisms. It is essential for understanding how genes are expressed, for discovering new gene variants and for understanding pathologies at the genetic level. RNA-Seq simulators are great for testing and validating bioinformatics tools, they offer a way to compare different computational algorithms and allow examining different sequencing protocols, parameter settings and sample sizes to ensure the most efficient use of resources. This study introduces BacSeqer, an RNA-Seq simulator specifically designed for bacterial transcriptomes with the aim of producing data that faithfully resembles those obtained in real experiments. It allows to take into account the specificities of the bacterial genome, especially an existence of only exons and their organization in operons that are not normally present in eukaryotes.en
dc.formattextcs
dc.format.extent12-15cs
dc.format.mimetypeapplication/pdfen
dc.identifier.citationProceedings II of the 30st Conference STUDENT EEICT 2024: Selected papers. s. 12-15. ISBN 978-80-214-6230-4cs
dc.identifier.doi10.13164/eeict.2024.12
dc.identifier.isbn978-80-214-6230-4
dc.identifier.issn2788-1334
dc.identifier.urihttps://hdl.handle.net/11012/249297
dc.language.isoencs
dc.publisherVysoké učení technické v Brně, Fakulta elektrotechniky a komunikačních technologiícs
dc.relation.ispartofProceedings II of the 30st Conference STUDENT EEICT 2024: Selected papersen
dc.relation.urihttps://www.eeict.cz/eeict_download/archiv/sborniky/EEICT_2024_sbornik_2.pdfcs
dc.rights© Vysoké učení technické v Brně, Fakulta elektrotechniky a komunikačních technologiícs
dc.rights.accessopenAccessen
dc.subjectRNA-Seqen
dc.subjectsimulationen
dc.subjectsequencingen
dc.subjectbacteriaen
dc.subjectgene expressionen
dc.titleBacSeqer: Read simulator for bacterial RNA-Seqen
dc.type.driverconferenceObjecten
dc.type.statusPeer-revieweden
dc.type.versionpublishedVersionen
eprints.affiliatedInstitution.departmentFakulta elektrotechniky a komunikačních technologiícs
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