Ultra-high-frequency ECG volumetric and negative derivative epicardial ventricular electrical activation pattern

Simple item page
dc.contributor.authorLeinveber, Pavelcs
dc.contributor.authorHalámek, Josefcs
dc.contributor.authorČurila, Karolcs
dc.contributor.authorPrinzen, Fritscs
dc.contributor.authorLipoldová, Jolanacs
dc.contributor.authorMatejková, Magdalénacs
dc.contributor.authorSmíšek, Radovancs
dc.contributor.authorPlešinger, Filipcs
dc.contributor.authorNagy, Andrejcs
dc.contributor.authorNovák, Miroslavcs
dc.contributor.authorViščor, Ivocs
dc.contributor.authorVondra, Vlastimilcs
dc.contributor.authorJurák, Pavelcs
dc.coverage.issue1cs
dc.coverage.volume14cs
dc.date.accessioned2024-05-14T06:45:27Z
dc.date.available2024-05-14T06:45:27Z
dc.date.issued2024-03-07cs
dc.description.abstractFrom precordial ECG leads, the conventional determination of the negative derivative of the QRS complex (ND-ECG) assesses epicardial activation. Recently we showed that ultra-high-frequency electrocardiography (UHF-ECG) determines the activation of a larger volume of the ventricular wall. We aimed to combine these two methods to investigate the potential of volumetric and epicardial ventricular activation assessment and thereby determine the transmural activation sequence. We retrospectively analyzed 390 ECG records divided into three groups-healthy subjects with normal ECG, left bundle branch block (LBBB), and right bundle branch block (RBBB) patients. Then we created UHF-ECG and ND-ECG-derived depolarization maps and computed interventricular electrical dyssynchrony. Characteristic spatio-temporal differences were found between the volumetric UHF-ECG activation patterns and epicardial ND-ECG in the Normal, LBBB, and RBBB groups, despite the overall high correlations between both methods. Interventricular electrical dyssynchrony values assessed by the ND-ECG were consistently larger than values computed by the UHF-ECG method. Noninvasively obtained UHF-ECG and ND-ECG analyses describe different ventricular dyssynchrony and the general course of ventricular depolarization. Combining both methods based on standard 12-lead ECG electrode positions allows for a more detailed analysis of volumetric and epicardial ventricular electrical activation, including the assessment of the depolarization wave direction propagation in ventricles.en
dc.formattextcs
dc.format.extent11cs
dc.format.mimetypeapplication/pdfcs
dc.identifier.citationScientific Reports. 2024, vol. 14, issue 1, 11 p.en
dc.identifier.doi10.1038/s41598-024-55789-wcs
dc.identifier.issn2045-2322cs
dc.identifier.orcid0000-0001-7267-4408cs
dc.identifier.orcid0000-0003-0413-3604cs
dc.identifier.other188371cs
dc.identifier.researcheridAAI-7788-2021cs
dc.identifier.researcheridF-5329-2017cs
dc.identifier.scopus57188873046cs
dc.identifier.urihttps://hdl.handle.net/11012/245511
dc.language.isoencs
dc.publisherNATURE PORTFOLIOcs
dc.relation.ispartofScientific Reportscs
dc.relation.urihttps://www.nature.com/articles/s41598-024-55789-wcs
dc.rightsCreative Commons Attribution 4.0 Internationalcs
dc.rights.accessopenAccesscs
dc.rights.sherpahttp://www.sherpa.ac.uk/romeo/issn/2045-2322/cs
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/cs
dc.subjectultra-high-frequency ECGen
dc.subjectUHF ECGen
dc.subjectnegative derivative mapen
dc.subjectepicardial activation mappingen
dc.titleUltra-high-frequency ECG volumetric and negative derivative epicardial ventricular electrical activation patternen
dc.type.driverarticleen
dc.type.statusPeer-revieweden
dc.type.versionpublishedVersionen
sync.item.dbidVAV-188371en
sync.item.dbtypeVAVen
sync.item.insts2024.05.14 08:45:27en
sync.item.modts2024.05.14 08:13:55en
thesis.grantorVysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií. Ústav biomedicínského inženýrstvícs
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
s4159802455789w.pdf
Size:
6.3 MB
Format:
Adobe Portable Document Format
Description:
file s4159802455789w.pdf
Download
Collections
Ústav biomedicínského inženýrství