Simulation of extrasystole in bidomain ventricular model with patient specific geometry

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but.event.date09.09.2023cs
but.event.titleTrendy v biomedicínském inženýrství 2023cs
dc.contributor.authorCocherová, Elena
dc.contributor.authorTyšler, Milan
dc.date.accessioned2023-10-23T08:02:51Z
dc.date.available2023-10-23T08:02:51Z
dc.date.issued2023cs
dc.description.abstractThe goal of the study was to simulate electrical activation on the heart ventricles and body surface potentials (BSP) during extrasystole using a realistic homogeneous model of cardiac ventricles and the patient torso. Electrical activation in the ventricular model was started in the known position of the initial ectopic activation confirmed by successful ablation in the left ventricle near the heart base as well as in several other sites near this position. The propagated electrical activation in the ventricular model was modeled using bidomain reaction-diffusion equations with the ionic transmembrane current density defined by the modified FitzHugh-Nagumo equations. The torso was treated as a homogeneous passive volume conductor. The whole simulation was numerically solved in the Comsol Multiphysics environment. Simulated BSP were compared with BSP measured in a real patient during extrasystole. The polarity and shape of selected simulated and measured ECG leads as well as the whole body surface potential distribution during the initial ectopic activation were in the best accordance when the stimulated region was close to the real position of the site of initial ectopic focus.en
dc.formattextcs
dc.format.extent50-55cs
dc.format.mimetypeapplication/pdfen
dc.identifier.citationProceedings of the Trendy v biomedicínském inženýrství 2023. s. 50-55. ISBN 978-80-214-6173-4cs
dc.identifier.doi10.13164/trendybmi.2023.50
dc.identifier.isbn978-80-214-6173-4
dc.identifier.orcid0000-0001-7653-287X
dc.identifier.orcid0000-0001-7674-0927
dc.identifier.urihttp://hdl.handle.net/11012/214372
dc.language.isoencs
dc.publisherVysoké učení technické v Brně, Fakulta elektrotechniky a komunikačních technologiícs
dc.relation.ispartofProceedings of the Trendy v biomedicínském inženýrství 2023en
dc.relation.urihttp://trendybmi.cz/konference/cs
dc.rightsCreative Commons Attribution 4.0 Internationalcs
dc.rights.accessopenAccessen
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/cs
dc.subjectbidomain refraction-diffusion modelen
dc.subjectrealistic ventricles and torso modelen
dc.subjectextrasystoleen
dc.subjectECGen
dc.subjectsimulationen
dc.subjectbody surface potentialsen
dc.titleSimulation of extrasystole in bidomain ventricular model with patient specific geometryen
dc.type.driverconferenceObjecten
dc.type.statusPeer-revieweden
dc.type.versionpublishedVersionen
eprints.affiliatedInstitution.departmentFakulta elektrotechniky a komunikačních technologiícs
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