A multi-color video-ophthalmoscopes allows to measure the spectral distribution of light absorption of blood in the human retina

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dc.contributor.authorTornow, Ralf-Petercs
dc.contributor.authorOdstrčilík, Jancs
dc.contributor.authorKolář, Radimcs
dc.coverage.issue1cs
dc.coverage.volume10cs
dc.date.accessioned2023-08-01T10:58:27Z
dc.date.available2023-08-01T10:58:27Z
dc.date.issued2023-03-16cs
dc.description.abstractBased on our previously developed mono-color video-ophthalmoscope a multi-color video-ophthalmoscope was developed. Using narrow band transmission filters, this instrument allows to measure the pulsatile cardiac cycle induced blood volume changes in the human retina for any wavelength in the sensitivity range of the used CMOS-camera. In this key experiment, video sequences (8 s, 25 fps, 200 frames) of the optic nerve head (ONH) were acquire for seven wavelengths between 475 nm and 677 nm one after the other. After image registration of all frames of each video sequence (to compensate for eye movements) and trend correction (to compensate for slow intensity changes), the amplitude of the cardiac cycle induced light intensity changes (pulsatile absorption amplitude PAA) can be calculated for all seven wavelengths. The results confirmed that the spectral distribution of PAA (lambda) follows the distribution of the light absorption of blood. The measured values correspond to the absorption of a thin blood layer of about 0.5 mu m thickness.en
dc.formattextcs
dc.format.extent1-6cs
dc.format.mimetypeapplication/pdfcs
dc.identifier.citationFrontiers in Medicine. 2023, vol. 10, issue 1, p. 1-6.en
dc.identifier.doi10.3389/fmed.2023.1125154cs
dc.identifier.issn2296-858Xcs
dc.identifier.orcid0000-0001-7053-6183cs
dc.identifier.orcid0000-0002-0469-6397cs
dc.identifier.other183401cs
dc.identifier.researcheridA-2237-2016cs
dc.identifier.researcheridC-8547-2014cs
dc.identifier.scopus35753651000cs
dc.identifier.urihttp://hdl.handle.net/11012/213626
dc.language.isoencs
dc.publisherFrontierscs
dc.relation.ispartofFrontiers in Medicinecs
dc.relation.urihttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10060599/pdf/fmed-10-1125154.pdfcs
dc.rightsCreative Commons Attribution 4.0 Internationalcs
dc.rights.accessopenAccesscs
dc.rights.sherpahttp://www.sherpa.ac.uk/romeo/issn/2296-858X/cs
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/cs
dc.subjectblood light absorptionen
dc.subjectphotoplethysmographyen
dc.subjectvideo ophthalmoscopyen
dc.subjectretinaen
dc.subjectmulti-color imagingen
dc.subjectretinal imagingen
dc.titleA multi-color video-ophthalmoscopes allows to measure the spectral distribution of light absorption of blood in the human retinaen
dc.type.driverarticleen
dc.type.statusPeer-revieweden
dc.type.versionpublishedVersionen
sync.item.dbidVAV-183401en
sync.item.dbtypeVAVen
sync.item.insts2023.08.01 12:58:27en
sync.item.modts2023.08.01 12:20:35en
thesis.grantorVysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií. Ústav biomedicínského inženýrstvícs
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