Hyaluronan-Arginine Interactions-An Ultrasound and ITC Study

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dc.contributor.authorJugl, Adamcs
dc.contributor.authorPekaƙ, Miloslavcs
dc.coverage.issue9cs
dc.coverage.volume12cs
dc.date.issued2020-09-12cs
dc.description.abstractHigh-resolution ultrasound spectroscopy and isothermal titration calorimetry were used to characterize interactions between hyaluronan and arginine oligomers. The molecular weight of arginine oligomer plays an important role in interactions with hyaluronan. Interactions were observable for arginine oligomers with eight monomer units and longer chains. The effect of the ionic strength and molecular weight of hyaluronan on interactions was tested. In an environment with increased ionic strength, the length of the arginine oligomer was crucial. Generally, sufficiently high ionic strength suppresses interactions between hyaluronan and arginine oligomers, which demonstrated interactions in water. From the point of view of the molecular weight of hyaluronan, the transition between the rod conformation and the random coil conformation appeared to be important.en
dc.formattextcs
dc.format.extent1-20cs
dc.format.mimetypeapplication/pdfcs
dc.identifier.citationPolymers. 2020, vol. 12, issue 9, p. 1-20.en
dc.identifier.doi10.3390/polym12092069cs
dc.identifier.issn2073-4360cs
dc.identifier.orcid0000-0003-0602-2334cs
dc.identifier.orcid0000-0002-3878-0917cs
dc.identifier.other165162cs
dc.identifier.urihttp://hdl.handle.net/11012/195577
dc.language.isoencs
dc.publisherMDPIcs
dc.relation.ispartofPolymerscs
dc.relation.urihttps://www.mdpi.com/2073-4360/12/9/2069cs
dc.rightsCreative Commons Attribution 4.0 Internationalcs
dc.rights.accessopenAccesscs
dc.rights.sherpahttp://www.sherpa.ac.uk/romeo/issn/2073-4360/cs
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/cs
dc.subjecthyaluronanen
dc.subjectarginineen
dc.subjectinteractionen
dc.subjecthigh-resolution ultrasound spectroscopyen
dc.subjectisothermal titration calorimetryen
dc.titleHyaluronan-Arginine Interactions-An Ultrasound and ITC Studyen
dc.type.driverarticleen
dc.type.statusPeer-revieweden
dc.type.versionpublishedVersionen
sync.item.dbidVAV-165162en
sync.item.dbtypeVAVen
sync.item.insts2025.02.03 15:38:50en
sync.item.modts2025.01.17 16:53:19en
thesis.grantorVysokĂ© učenĂ­ technickĂ© v Brně. Fakulta chemickĂĄ. Ústav fyzikĂĄlnĂ­ a spotƙebnĂ­ chemiecs
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Ústav fyzikální a spotƙební chemie