Facile Preparation of Porous Microfiber from Poly-3-(R)-Hydroxybutyrate and Its Application

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dc.contributor.authorKundrát, Vojtěchcs
dc.contributor.authorSkoumalová, Petracs
dc.contributor.authorMárová, Ivanacs
dc.coverage.issue1cs
dc.coverage.volume13cs
dc.date.issued2020-01-20cs
dc.description.abstractIn this study, we described the development of a simplified wet spinning method of the production of a novel type of porous continuous fiber based on poly-3-(R)-hydroxybutyrate (PHB). The principle of this method is precipitation of PHB dissolved in chloroform solution into the ethanol precipitation bath. The influence of various PHB concentrations and feed rates on specific surface area (measured by nitrogen absorption method) was studied. Materials were also characterized by SEM. Surface areas of fibers achieved by wet spinning were in the range of tens of m(2).g(-1), and the biggest surface area value was 55 m(2).g(-1). The average diameter of fibers was in the range of 20-120 mu m and was dependent on both PHB concentration and feed rate. Optimum conditions for reaching stable fibers of high surface area were 3-5 % w.t. of PHB and feed rate 0.5-3 ml.h(-1). Fibers were functionalized by adsorption of some natural plant extracts. The incorporation of active substances into fibers was confirmed by infrared spectroscopy. High antioxidant and antimicrobial effect of PHB-fibers with cloves extract was found, as well as excellent long-term stability and optimal dynamics of the release of active compounds. The newly produced material would be applicable in pharmacy, cosmetics, and wound healing.en
dc.description.abstractIn this study, we described the development of a simplified wet spinning method of the production of a novel type of porous continuous fiber based on poly-3-(R)-hydroxybutyrate (PHB). The principle of this method is precipitation of PHB dissolved in chloroform solution into the ethanol precipitation bath. The influence of various PHB concentrations and feed rates on specific surface area (measured by nitrogen absorption method) was studied. Materials were also characterized by SEM. Surface areas of fibers achieved by wet spinning were in the range of tens of m(2).g(-1), and the biggest surface area value was 55 m(2).g(-1). The average diameter of fibers was in the range of 20-120 mu m and was dependent on both PHB concentration and feed rate. Optimum conditions for reaching stable fibers of high surface area were 3-5 % w.t. of PHB and feed rate 0.5-3 ml.h(-1). Fibers were functionalized by adsorption of some natural plant extracts. The incorporation of active substances into fibers was confirmed by infrared spectroscopy. High antioxidant and antimicrobial effect of PHB-fibers with cloves extract was found, as well as excellent long-term stability and optimal dynamics of the release of active compounds. The newly produced material would be applicable in pharmacy, cosmetics, and wound healing.cs
dc.formattextcs
dc.format.extent1-14cs
dc.format.mimetypeapplication/pdfcs
dc.identifier.citationMaterials . 2020, vol. 13, issue 1, p. 1-14.en
dc.identifier.doi10.3390/ma13010086cs
dc.identifier.issn1996-1944cs
dc.identifier.orcid0000-0003-4705-7752cs
dc.identifier.orcid0000-0002-2095-1837cs
dc.identifier.other161667cs
dc.identifier.researcheridA-6994-2016cs
dc.identifier.researcheridA-6897-2016cs
dc.identifier.scopus56477418300cs
dc.identifier.scopus6603465110cs
dc.identifier.urihttp://hdl.handle.net/11012/195648
dc.language.isoencs
dc.publisherMDPIcs
dc.relation.ispartofMaterialscs
dc.relation.urihttps://doi.org/10.3390/ma13010086cs
dc.rightsCreative Commons Attribution 4.0 Internationalcs
dc.rights.accessopenAccesscs
dc.rights.sherpahttp://www.sherpa.ac.uk/romeo/issn/1996-1944/cs
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/cs
dc.subjectP-3-HBen
dc.subjectPHBen
dc.subjectwet spinningen
dc.subjectmicrofiberen
dc.subjectporesen
dc.subjectP-3-HB
dc.subjectPHB
dc.subjectwet spinning
dc.subjectmicrofiber
dc.subjectpores
dc.titleFacile Preparation of Porous Microfiber from Poly-3-(R)-Hydroxybutyrate and Its Applicationen
dc.title.alternativeFacile Preparation of Porous Microfiber from Poly-3-(R)-Hydroxybutyrate and Its Applicationcs
dc.type.driverarticleen
dc.type.statusPeer-revieweden
dc.type.versionpublishedVersionen
sync.item.dbidVAV-161667en
sync.item.dbtypeVAVen
sync.item.insts2025.02.03 15:38:03en
sync.item.modts2025.01.17 18:46:46en
thesis.grantorVysoké učení technické v Brně. Fakulta chemická. Fakulta chemickács
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