Prediction of localized aerosol deposition in a realistic replica of human airways using experimental data and numerical simulation

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dc.contributor.authorLízal, Františekcs
dc.contributor.authorElcner, Jakubcs
dc.contributor.authorBělka, Miloslavcs
dc.contributor.authorJedelský, Jancs
dc.contributor.authorJícha, Miroslavcs
dc.coverage.volume143cs
dc.date.issued2016-11-15cs
dc.description.abstractThe presence of aerosol deposition hot-spots in human airways presumably contributes to development of various diseases. The overall aerosol deposition in human lungs can be predicted with sufficient accuracy nowadays. However, the prediction of localized aerosol deposition poses arduous challenge, namely in diseased lungs. Numerical simulation is considered to be a promising tool for the successful prediction. Yet, the validation of such simulations is difficult to perform, as not enough experimental data acquired using realistic airway replicas is available. This paper presents a first comparison of localized deposition measurement and simulation performed on the identical realistic geometry. The analysis indicates that both approaches yield similar results for low Reynolds number flows.en
dc.formattextcs
dc.format.extent1-4cs
dc.format.mimetypeapplication/pdfcs
dc.identifier.citationEPJ Web of Conferences. 2016, vol. 143, p. 1-4.en
dc.identifier.doi10.1051/epjconf/201714302067cs
dc.identifier.issn2100-014Xcs
dc.identifier.orcid0000-0002-0389-608Xcs
dc.identifier.orcid0000-0001-9287-4458cs
dc.identifier.orcid0000-0001-8905-9751cs
dc.identifier.orcid0000-0002-1268-8434cs
dc.identifier.orcid0000-0002-1409-5165cs
dc.identifier.other131497cs
dc.identifier.researcheridD-4363-2018cs
dc.identifier.researcheridI-3748-2018cs
dc.identifier.researcheridA-9224-2013cs
dc.identifier.researcheridCVT-7747-2022cs
dc.identifier.scopus54966786300cs
dc.identifier.scopus55090074500cs
dc.identifier.scopus23090535800cs
dc.identifier.scopus6602494673cs
dc.identifier.urihttp://hdl.handle.net/11012/70127
dc.language.isoencs
dc.publisherEDP Sciencescs
dc.relation.ispartofEPJ Web of Conferencescs
dc.relation.urihttps://www.epj-conferences.org/articles/epjconf/abs/2017/12/epjconf_efm2017_02067/epjconf_efm2017_02067.htmlcs
dc.rightsCreative Commons Attribution 4.0 Internationalcs
dc.rights.accessopenAccesscs
dc.rights.sherpahttp://www.sherpa.ac.uk/romeo/issn/2100-014X/cs
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/cs
dc.subjectaerosol depositionen
dc.subjecthuman lungsen
dc.subjecthuman airwaysen
dc.subjectcomputational fluid mechanicsen
dc.subjectexperimenten
dc.titlePrediction of localized aerosol deposition in a realistic replica of human airways using experimental data and numerical simulationen
dc.type.driverconferenceObjecten
dc.type.statusPeer-revieweden
dc.type.versionpublishedVersionen
sync.item.dbidVAV-131497en
sync.item.dbtypeVAVen
sync.item.insts2025.02.03 15:47:17en
sync.item.modts2025.01.17 16:38:09en
thesis.grantorVysoké učení technické v Brně. Fakulta strojního inženýrství. EÚ-odbor termomechaniky a techniky prostředícs
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