Signal Based Processing Of Metagenomic Data From Nanopore Sequencing

Abstract

The revolutionary sequencing technology introduced by Oxford Nanopore Technologies – MinION holds a great promise in the field of metagenomics due to its low cost, produced long reads and small size, which makes it available also for field work. The only problem preventing this technology from reaching its full potential is the lack of available computational tools for handling the produced data. Here we present an algorithm for processing of the raw signal sequences generated by nanopore sequencing for metagenomic purposes allowing to remove viral sequences from a contaminated metagenomic sample.