Johann Gregor Mendel: the victory of statistics over human imagination

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dc.contributor.authorRaudenská, Martinacs
dc.contributor.authorVičar, Tomášcs
dc.contributor.authorGumulec, Jaromírcs
dc.contributor.authorMasařík, Michalcs
dc.coverage.issue7cs
dc.coverage.volume31cs
dc.date.issued2023-02-09cs
dc.description.abstractIn 2022, we celebrated 200 years since the birth of Johann Gregor Mendel. Although his contributions to science went unrecognized during his lifetime, Mendel not only described the principles of monogenic inheritance but also pioneered the modern way of doing science based on precise experimental data acquisition and evaluation. Novel statistical and algorithmic approaches are now at the center of scientific work, showing that work that is considered marginal in one era can become a mainstream research approach in the next era. The onset of data-driven science caused a shift from hypothesis-testing to hypothesis-generating approaches in science. Mendel is remembered here as a promoter of this approach, and the benefits of big data and statistical approaches are discussed.en
dc.formattextcs
dc.format.extent744-748cs
dc.format.mimetypeapplication/pdfcs
dc.identifier.citationEUROPEAN JOURNAL OF HUMAN GENETICS. 2023, vol. 31, issue 7, p. 744-748.en
dc.identifier.doi10.1038/s41431-023-01303-1cs
dc.identifier.issn1018-4813cs
dc.identifier.orcid0000-0002-9136-7873cs
dc.identifier.orcid0000-0002-9658-3444cs
dc.identifier.other183274cs
dc.identifier.researcheridC-6006-2018cs
dc.identifier.researcheridD-7638-2012cs
dc.identifier.scopus57202426072cs
dc.identifier.scopus55769747816cs
dc.identifier.urihttp://hdl.handle.net/11012/244279
dc.language.isoencs
dc.publisherSpringer Naturecs
dc.relation.ispartofEUROPEAN JOURNAL OF HUMAN GENETICScs
dc.relation.urihttps://www.nature.com/articles/s41431-023-01303-1cs
dc.rightsCreative Commons Attribution 4.0 Internationalcs
dc.rights.accessopenAccesscs
dc.rights.sherpahttp://www.sherpa.ac.uk/romeo/issn/1018-4813/cs
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/cs
dc.subjectDeep learning frameworken
dc.subjectbig dataen
dc.subjectdata scienceen
dc.subjecthumanen
dc.subjecthuman experimenten
dc.subjectimaginationen
dc.subjectmaleen
dc.subjectMendelian inheritanceen
dc.subjectpromoter regionen
dc.subjectreviewen
dc.titleJohann Gregor Mendel: the victory of statistics over human imaginationen
dc.type.driverarticleen
dc.type.statusPeer-revieweden
dc.type.versionpublishedVersionen
sync.item.dbidVAV-183274en
sync.item.dbtypeVAVen
sync.item.insts2025.02.10 16:19:39en
sync.item.modts2025.02.09 17:32:03en
thesis.grantorVysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií. Ústav biomedicínského inženýrstvícs
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