An Influence Of Physical Electrode Models In Rat’S Head Forward Modelling

Abstract

Reliable inverse imaging of source currents in rat’s brain requires moderate models of fields to calibrate inverse solvers. The article is focused on the comparison of measured potentials on rat’s brain surface with and without physical electrode models. For the simulation purpose, the 3D models of the brain, the cerebrospinal fluid, and the skull were developed from magnetic resonance images (MRI). Moreover, the pink noise was added to measured potentials to obtain more realistic results. Simulations showed higher values of potentials when physical electrode models were considered. Fortunately, the presence of electrode models does not influence the potential waveform. Therefore, the inclusion of electrode models to forward modelling can contribute to the increase of accuracy of an inverse solver, and thus the localization of current sources in rat’s brain.