Feature-overlapper: The tool for DNA analysis overlap
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Date
2023-05-01
Authors
Havlík, Jan
Brázda, Václav
Staněk, Kamil
Ježek, Michal
Šťastný, Jiří
0000-0003-2837-4226Advisor
Referee
Mark
Journal Title
Journal ISSN
Volume Title
Publisher
Elsevier
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Abstract
This contribution puts focus on a command line tool, which enables detection and analysis of overlapping regions between G-quadruplexes, R-loops and genome annotations for selected genomes. G-quadruplexes and R-loops are structures with high Guanine density, which is an important creation factor for both structures. Common regions (overlap) between both structures can provide us with better possibility to create precise model to detect R-loops and valuable insights when inspecting genome annotations with high R-loop density. The tool was used for multiple research projects and is under constant development bringing new features to the world of bioinformatics.
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Citation
Software Impacts. 2023, vol. 16, issue 5, p. 1-4.
https://www.sciencedirect.com/science/article/pii/S2665963823000350?via%3Dihub
https://www.sciencedirect.com/science/article/pii/S2665963823000350?via%3Dihub
Document type
Peer-reviewed
Document version
Published version
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Language of document
en