Effect of the selected phenolic and flavonoid compounds of black pepper and caraway seeds on prostate cells

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dc.contributor.authorLacková, Zuzanacs
dc.contributor.authorBuchtelová, Hanacs
dc.contributor.authorBuchtová, Žanetacs
dc.contributor.authorAdam, Vojtěchcs
dc.contributor.authorZítka, Ondřejcs
dc.date.accessioned2018-08-23T10:52:55Z
dc.date.available2018-08-23T10:52:55Z
dc.date.issued2017-12-31cs
dc.description.abstractIn this study, the effect of selected phenolic and flavonoid compounds of black pepper and caraway seeds on prostate cells (PNT1A, 22RV1 and PC3) was observed. Synthetic standards of 3,4-dihydroxybenzaldehyde and naringenin chalcone, identified previously by HPLC-MS in black pepper seeds extracts, and neochlorogenic acid and apigenin, identified in caraway seeds extracts, were applied. For the evaluation of the potential inhibitory effect of selected compounds on PNT1A, 22RV1 and PC3 cells, the clonogenic assay and the microscopic observation of cells were done. The results of clonogenic assay showed that phenolic compounds had the strongest inhibitory effect on 22RV1 and PC3 cells, while the flavonoid compounds had the strongest inhibitory effect on PNT1A cells.en
dc.formattextcs
dc.format.extent900-904cs
dc.format.mimetypeapplication/pdfcs
dc.identifier.citationMendelNet 2017. 2017, p. 900-904.en
dc.identifier.isbn978-80-7509-529-9cs
dc.identifier.other148746cs
dc.identifier.urihttp://hdl.handle.net/11012/84188
dc.language.isoencs
dc.publisherMendel University in Brnocs
dc.relation.ispartofMendelNet 2017cs
dc.relation.urihttps://mendelnet.cz/artkey/mnt-201701-0103_Effect-of-the-selected-phenolic-and-flavonoid-compounds-of-black-pepper-and-caraway-seeds-on-prostate-cells.php?back=/magno/mnt/2017/mn1.php?secid=4cs
dc.rights(C) Mendel University in Brnocs
dc.rights.accessopenAccesscs
dc.subjectSpicesen
dc.subjectclonogenic assayen
dc.subjectphenolic compoundsen
dc.subjectflavonoid compoundsen
dc.subjectprostate cell linesen
dc.titleEffect of the selected phenolic and flavonoid compounds of black pepper and caraway seeds on prostate cellsen
dc.type.driverconferenceObjecten
dc.type.statusPeer-revieweden
dc.type.versionpublishedVersionen
sync.item.dbidVAV-148746en
sync.item.dbtypeVAVen
sync.item.insts2020.04.01 11:01:49en
sync.item.modts2020.04.01 05:49:36en
thesis.grantorVysoké učení technické v Brně. Středoevropský technologický institut VUT. Chytré nanonástrojecs
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