Zinc phosphate nanoparticles as an antimicrobial agent and their impact on rats microbiota
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Date
2019-01-02
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Referee
Mark
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Mendel University in Brno
Abstract
Nano minerals, especially trace minerals, are widely used in different fields, but mostly in
animal systems. They can improve overall immunity and also a digestive efficacy in livestock. In this
case, nanometals as nano mineral substances were synthetized, particular the zinc phosphate-based
nanoparticles (ZnNPs). The antibacterial activity against three bacterial strains – E. coli, S. aureus and
methicillin-resistant S. aureus was determined using different methods. After promising in vitro testing,
the impact of these zinc nanoparticles on rats after oral exposure during 30 days of treatment was
investigated. The antibacterial effects on rats gut microbiota were monitored, with the aim to reduce the
number of pathogenic bacteria.
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Peer-reviewed
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Published version
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en
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(C) Mendel University in Brno