Využití 3D tisku pro studium cév

Abstract

Táto diplomová práca je zameraná na využitie 3D tlače pre štúdium ciev. Pre účely tejto práce boli zvolené dve techniky 3D tlače, SLA a FDM, kde sa optimalizovali podmienky tlače. V rámci experimentálnej časti práce boli najskôr vytlačené modely štyroch druhov kostí a štyroch aneuryziem. Ďalej sa vyhodnocoval charakter prúdenia častíc v oblasti strednej mozgovej tepny so stenózou. Potvrdilo sa, že najväčší prietok je v oblasti so stenózou, kde sa mení laminárny prietok na turbulentný. Ďalším krokom bolo pozorovanie uhla zmáčania na modifikovaných povrchoch živíc a silikónu. Oba povrchy boli najskôr modifikované plazmou, ktorá ich zmenila z hydrofóbneho na hydrofilný. Živice boli ešte upravované pomocou 5% a 10% NaOH. Po tejto úprave sa hydrofilný povrch v prípade 10% NaOH stal superhydrofilným a uhol zmáčania bolThis Master‘s thesis deals with the use of 3D printing for a vasculature study. For the purposes of this work, two 3D printing techniques were chosen, SLA and FDM, where the printing parameters were optimized. In the experimental part of the work, models of four types of bones and four aneurysms were printed. Furthermore, the flow of particles in the area of the middle cerebral artery with stenosis was evaluated. It was confirmed that the highest flow is in the area with stenosis, where the laminar flow changes to turbulent. The next step was to observe the wetting angle on the modified resin and silicone surfaces. Both surfaces were first modified with air plasma, which changed them from hydrophobic to hydrophilic. The resins were further treated with 5% and 10% NaOH. After this treatment, the hydrophilic surfaces became superhydrophilic in the case of 10% NaOH and the wetting angle was