Maghemite particles for spermidine separation

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dc.contributor.authorKopel, Pavelcs
dc.contributor.authorCernei, Natalia Vladimirovnacs
dc.contributor.authorHorký, Pavelcs
dc.contributor.authorLacková, Zuzanacs
dc.contributor.authorMilosavljević, Vedrancs
dc.contributor.authorGagić, Milicacs
dc.contributor.authorZítka, Ondřejcs
dc.contributor.authorAdam, Vojtěchcs
dc.date.accessioned2021-05-04T10:54:19Z
dc.date.available2021-05-04T10:54:19Z
dc.date.issued2020-06-10cs
dc.description.abstractWe report the optimal conditions for the separation of spermidine from different types of samples, for example blood or cancer cells and its subsequent determination by ion-exchange liquid chromatography (IEC) with UV-VIS detector. Here in, we synthesized paramagnetic particles able to isolate and immobilize spermidine from blood of patients with cancer or cancer cells and thus preconcentrate it for analysis. Dowex surface was covered by nanomaghemite (-Fe2O3) or maghemite particles surface was modified by chitosan and sulfoxyethyl cellulose. The best separation properties showed Dowex microparticles. The paramagnetic particles can be used in the future for isolation of spermidine from real samples and diagnosis of cancer.en
dc.formattextcs
dc.format.extent353-357cs
dc.format.mimetypeapplication/pdfcs
dc.identifier.citationNANOCON 2019 CONFERENCE PROCEEDINGS. 2020, p. 353-357.en
dc.identifier.doi10.37904/nanocon.2019.8496cs
dc.identifier.isbn978-80-87294-95-6cs
dc.identifier.other164258cs
dc.identifier.urihttp://hdl.handle.net/11012/196671
dc.language.isoencs
dc.publisherTangercs
dc.relation.ispartofNANOCON 2019 CONFERENCE PROCEEDINGScs
dc.relation.urihttps://doi.org/10.37904/nanocon.2019.8496cs
dc.rightsCreative Commons Attribution 4.0 Internationalcs
dc.rights.accessopenAccesscs
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/cs
dc.subjectIon exchange chromatographyen
dc.subjectmaghemiteen
dc.subjectspermidineen
dc.subjectchitosan and sulfoxyethyl celluloseen
dc.titleMaghemite particles for spermidine separationen
dc.type.driverconferenceObjecten
dc.type.statusPeer-revieweden
dc.type.versionpublishedVersionen
sync.item.dbidVAV-164258en
sync.item.dbtypeVAVen
sync.item.insts2021.05.04 12:54:19en
sync.item.modts2021.05.04 12:14:37en
thesis.grantorVysoké učení technické v Brně. Středoevropský technologický institut VUT. Chytré nanonástrojecs
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